Next time you need to get tested for breast cancer, doctors may blast a few of your cells with nanoparticles and then run a small magnetic device over them. The device, pictured here, is called a HistoMag, and it can detect cancer cells with far greater accuracy than current techniques, as well as being much faster. Could this increase survival rates for breast cancer, while also eliminating the need for those awful, uncomfortable mammograms?
It's very possible. Quentin Pankhurst, a physics professor at the University College of London, says:
Until now, pathologists had to stain tissue samples with brown dyes to help them determine whether they were normal or cancerous. In terms of streamlining the process, the main problem is that all of the results are open to interpretation and each test has to be individually checked by a specialist . . . We've been working in the relatively new area of biomagnetics to develop a technique which provides more quantitative and reliable results, whilst also enabling pathologists to identify abnormal tissue sections much more quickly.We look forward to our first nano-boob tests.Cancerous cells have a protein on their surface called HER2. We use a solution of HER2 antibodies, tagged with magnetic nanoparticles, to stain the tissue sample. Using the HistoMag we can detect the quantity of tagged antibodies which attach themselves to the HER2 protein, which in turn provides us with an accurate picture of the spread of cancerous cells.
HistoMag, a Magnetometer for Cancer Cells [MedGadget]













Comments
heh, nano-boob.
Magic indeed; this is the breast news I've heard all day.
Puns aside, thanks for the amazing news...I'm hoping that breast cancer treatment makes huge leaps in the next few years since my mom had a double mastectomy. They can save your life if they catch it in time, but I don't want to lose my breasts. Taking a woman's breasts away to spite her cancer seems really primitive to me.
Brown dyes? (he's likely talking about immunohistochemistry). That said, that's a very cool development. It's good for HER2 positive tumours but I would imagine they are looking for other markers for other tumour types.
Any non-invasive accurate cancer test is a good thing. Encourages people to get tested and the early the detection the better.
It sounds like this is aimed more finding positive lymph nodes that something else. (it mentions "which in turn provides us with an accurate picture of the spread of cancerous cells.")
And while it might better than the current method of finding positive lymph nodes...
I doubt it will make much difference for the "specialist".
-signed the specialist.
@hikergirl: Yeah he is talking about Immunohistochemistry. The reason why thye are looking at HER2, is the same reason why it might no work for other markers.. HER2 is a surface antigen. This test is unlikely to work well in vivo on anything other than surface antigens...
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