Will the Neo-Depression Create a Drug Epidemic? Many economic crisis periods in the U.S. have spawned drug epidemics. During the late-nineteenth century "long depression" or "crisis," the use of opium reached epidemic proportions, and a few decades later the innovation of intravenous injection made heroin the drug of choice among 1930s Depression-era junkies. Heroin made a comeback during the 1973 Oil Crisis, while cocaine and crack use spiked directly after the early 1980s Recession. Meth was the drug of choice during the early 1990s recession, and we're sure to get another dose as the Neo-Depression of the early twenty-first century marches on. We've got some ideas about what drug it might be — and you can offer your opinion in our poll below.