The bulbous blue-headed supervillain comedy Megamind may seem like just another superhero retread cartoon, but the brand new trailer proves its comedic merit. Plus Tina Fey is wickedly clever as the unimpressed damsel-in-distress. Watch and laugh. Minor spoilers below.

Interesting side note - this isn't even the entire movie. The trailer is basically setting up the first half of the film, if even that much. The synopsis spoils what happens to Metro Man, so if you want to know read on:

After super-villain Megamind (Will Ferrell) kills his good-guy nemesis, Metro Man (Brad Pitt), he becomes bored since there is no one left to fight. He creates a new foe, Titan (Jonah Hill), who, instead of using his powers for good, sets out to destroy the world, positioning Megamind to save the day for the first time in his life.

Megamind will be in theaters November 5th, 2010.

[via Yahoo]