Speaking of completely improbable comic book crossovers, here's something completely different. This May, IDW Publishing will release an Eleventh Doctor/The Next Generation mash-up comic book starring The Doctor, Rory, Amy, Picard, Worf, Data, Geordi, Troi, and Riker. Holy baloney, this has the potential to be even crazier than the time Wolverine drank all that prune juice with Whoopi Goldberg.
This crossover comes on the tail of the equally "who'd have thunk" Star Trek/Legion of Superheroes. Details are scant for the time being, but here's the cover. Hypothesize wildly in the comments as to what the plot will be! I've got more than few Quatloos on Tribbles versus The Adipose.
Via Bleeding Cool - hat tip to Ursus-Veritas!