Here's what happened in the Firefly universe after Serenity

Writer Zack Whedon has spilled the beans on where the crew of the Serenity will find themselves when Dark Horse releases the sequel comic, subtitled Leaves in the Wind, this January: the crew is on the run (of course), the Alliance is still in charge, Jayne is missing, and Zoe is pregnant. BABY WASH, PEOPLE.

Whedon reveals this and more in an interview with Comic Book Resources. Here's the main deal:

It has been around nine months since the conclusion of "Serenity." A lot has changed and a lot has stayed the same. The discovery that Mal and his crew shared with the 'verse — that the inhabitants of the planet Miranda were killed or driven mad by an Alliance experiment — has opened some eyes and created some new allies, but it hasn't deterred any of their pursuers. If anything, it has made them more relentless. Serenity is hiding out in lesser-known corners of the 'verse, trying to keep a low profile. As you will see early on, that's easier said than done. Mal and his crew will be forced to face their enemies head on — some familiar, some new.

Since the comic picks up nine months later, the crew has had time to deal with their grief regarding Wash and Book, and if nothing else at least River is doing pretty well. The whole interview is packed with tidbits, if you're interested. Here's my favorite line, courtesy of CBR's intro:

This comic is shaping up to be, in many ways, a departure from the sometimes light-hearted series.

Can it possibly be less light-hearted than Serenity? If everyone on the ship gets space cancer, we riot.