What's The Weirdest Comic Book Adaptation Of All Time?

Everybody knows it's hard to convert comics to movies, TV or prose fiction. There's just something about the dynamic storytelling in comics that's hard to capture in other media. But what's the most bizarre comics adaptation of all time?

Please include a picture or clip (or book cover) for your chosen weird adaptation. And please mention the name, and what was strange about it. Thanks!

Top image: Howard the Duck, still one of the oddest movies I've ever seen.