Feros bummed me out for a bit in the start too. The game is also an RPG in the sense that it doesn't limit too much where to go at the start, and does allow you to go to places that are over your head. If you are having too much trouble, then the best thing to do is to fly around and do some sidequests. What can seem impossible at start will be a cakewalk after a few levels. Though I did manage to pass Feros eventually the first time round without settling on that solution. The Thorian Creepers are stupid and clumsy, and you can hold them off by picking a standpoint where only a couple can get at you at a time, and take them out one by one, punching those that get too close (they fly like ragdolls), and keeping the others in check with biotics.
It requires a bit more active tactical thinking than ME2 I think, though the less than stellar cover mechanics and the fact that you don't always hit where the reticule shows without enough skill points can make it frustrating at times.
The quarians' plight? Battlestar Galactica. The Spectres? Lensmen. The Rachni? Starship Troopers crossed with Ender's Game. The turian society is heavily inspired by Starship Troopers, too. The Reapers? Very much like the Inhibitors from Alastair Reynolds's Revelation Space, though those are hardly the only civilization-destroying sentient machines, either.
And you are way off mark if you imagine that the Keepers of all things were inspired by the Shadows. Apart from being insectoid, there's absolutely nothing similar about them, and scifi is filled with insectoid races. The Keepers are slaves, the Shadows are their own masters. The Keepers are nearly mindless automatons, the Shadows are hyperintelligent, self-styled guides of cosmic evolution. The Keepers are green and soft-angled, the Shadows are black (when visible at all) and filled with jagged edges.
Now the Collector General's distinct head shape does have some vague resemblance to the Shadow design, but the Collectors are extremely different from the Shadows in motivation, origin and nature.
The core plotline has little in common with Babylon 5, in any case. Ancient evil awakes, an interstellar alliance must be formed to stop it. That's just about it, and I can assure you that B5 didn't invent the formula. The nature of this evil is totally different from B5, where the whole thing was revealed to be just a smokescreen for an ideological zero-sum game between two ancient races, and there was never any intent to destroy civilizations, just to demonstrate that fear and conflict make them stronger. The relentless Reaper invasion out to destroy all galactic civilizations as a part of their reproduction cycle is a completely different ball-game.
In a nutshell, you are wrong. Mass Effect took influence from a wide variety of sources, as did Babylon 5, and you imagine that Mass Effect swiped its plot from B5 because both took influence from the same sources.
Also, removing lapels and neckties is the next obvious step in the evolution of formalwear; compare late 19th century fashion, 1950's fashion and today's fashion and see the trend. Though in Mass Effect universe the graphical designers didn't leave things to that, and added plenty of orginal touches to the future fashions. Just look at Anderson's Councillor's suit in ME2 and tell that you ever saw anything like it in Babylon 5.
ME1 has, in my opinion, better paced plot than ME2, which was essentially a long collection of loosely related sidequests, albeit very high quality ones. There's a very clear act structure, and a straightforward goal always ahead of you. I seriously recommend playing the game just to get a full experience.
They should go for the prequel route like this fan group has done. I think that the humanity's ascent would make an excellent theatrical story, though it would work even better as a high-budget miniseries; a movie would probably have to be focused on the First Contact War alone, while a miniseries could track every important moment from the discovery of the Mars cache to finding of the human embassy on the Citadel.
Ofcourse you'd first have to find a scientist interested in running into office anyway. For most that would be a pointless distraction from doing actual science.
Existence is complex and we're always finding more layers to peel in it, but what it all has in common is that force has effect even when it's not directly visible. Hence why I'm not accepting that there could be a higher order of universe impossible to trace. If it's there, then its forces influence the universe as we know it, and we can extrapolate information from them.
If you thought that I'd be arguing for a universe with a clear beginning, end, meaning or purpose, you are mistaken. Again, those concepts tell more about how humans perceive the world than what the universe is actually like.
Study of stars, study of molecules, study of minds, they're all part of the same basic goal of understanding our surroundings a little better. I'm a transhumanist, and hope that the study of minds will illuminate ways to improve our own to make better sense of the rest of it, but it's just one worthy goal among many. Focusing on it too much may lead to narcissism or solipsism.