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mad genetic engineering
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mad genetic engineering
mad science art
Curator Forced to Kill Out-of-Control Bio-Art Exhibit
The problem with bio-art is that it's often made of living tissue — and sometimes living tissue gets out of control. That's what happened late last week at a New York MoMA exhibit called "Design and the Elastic Mind," where a tiny living jacket made out of stem cells had to be put to death for growing too fast and trying to burst out of its container. More »
splice
Hard Scifi Flick "Splice" Actually Based on Internet-Rumor Science
Turns out that the hard science underpinning Splice, a forthcoming flick about genetic engineering directed by Vincenzo "Cube" Natali, is actually not so hard. In a recent interview, the director claims his inspiration to do a genetic chimera movie was seeing a now-famous image of a mouse with a human ear grafted onto its back. "It was such a crazy, shocking weird image that I was inspired to write a story about genetic splicing," he said. Unfortunately, what he saw wasn't genetic splicing at all. More »
bio-art
Bio-Artist Will Not Go to Jail
Using bacteria and harmless biological materials to whip up bio-art projects in your living room is not against the law, a U.S. district court determined yesterday. The decision marked the end of a four-year ordeal for artist Steve Kurtz, who was arrested in 2004 when his wife died and police arrived to discover petri dishes and other "suspicious" lab equipment in Kurtz's home. The equipment was for a show he and his wife had been prepping for a show about GMO foods at a Boston museum, but police confiscated it and detained Kurtz in jail anyway. More »
mad science
Double Your Lifespan with a Drug that Mutates Your Ribosomes
It's been known for a while that restricting your diet will increase your lifespan, but now researchers have shown one reason why: Eating less causes your ribosomes (your cells' protein factories) to mutate. And it's looking like mutated ribosomes (pictured here) could be one key to life extension. The good news is that you may not have to starve yourself to mutate your ribosomes anymore. Biologists at the University of Washington have managed to induce the life-extending mutation in ribosomes with a drug that doubles the lifespan of yeast cells. More »
ask a biogeek
Where Is My Medical Tricorder?
Reader Juan asks:If not the medical tricorder from Star Trek, when could we possibly see diagnostic equipment capable of scanning for infections, viruses or impending heart attacks, attached to wrist watches or other portable devices?Nothing against the phaser, but for many of us the most coveted piece of away team equipment is the tricorder, the medical version of which can perform a complex examination in a single whistling pass over a patient. If you've ever tried to lie perfectly still in a thumping MRI machine or sat in a doctor's office waiting for lab results, you've longed for faster, more portable diagnostic devices. More »
9:00 AM on Thu Apr 17 2008
By Terry Johnson
1,598 views,
18 comments
Latest by the_wiggle: @Gyrus: want! also, self cleaning clothes & home; plus flying car ;) more »
tissue engineering
Vat-Grown Meat About to Hit Your Local Market
In five years, you'll be eating a hamburger that no animal died for. Instead, that burger will have been grown from a tiny sample of cells in a plant-and-mushroom bath. The cow who donated the cells will be frolicking in a meadow somewhere, having long forgotten the annoying poke from a tissue engineer with a syringe. At a meeting in Norway of the In Vitro Meat Consortium late last week, scientists and entrepreneurs gathered to discuss the future of "cultured meat," or meat that's essentially grown like cultures in a lab (pictured here). This meeting, the first of its kind, signaled the beginning of a viable industry around the production of vat-grown meat. More »
splicers
Splicers Goes Back to the Old Human-Animal Intermingling Formula
All those headlines about geneticists creating "chimeras" in the lab — mingling human and animal DNA for experiments — have finally spawned a new flick. But Splicers, coming out next year with stars Adrian Brody and Sarah Polley as beleaguered DNA mixers, isn't exactly the cool movie one might have hoped for. More »
ask a biogeek
Welcome to Ask a Biogeek, a column about cutting-edge biology by UC Berkeley researcher Terry Johnson. Knowing which organs you can live without is all well and good, but wouldn't you rather have replacement organs? Tissue engineers already have some pretty good ones if you happen to lose your skin or severely damage your bones. And there are some other organs we're cooking up for you too, as long as you can hold out for a few more years.
More »
Forget the Jetpack - Where Are My Replacement Organs?
Welcome to Ask a Biogeek, a column about cutting-edge biology by UC Berkeley researcher Terry Johnson. Knowing which organs you can live without is all well and good, but wouldn't you rather have replacement organs? Tissue engineers already have some pretty good ones if you happen to lose your skin or severely damage your bones. And there are some other organs we're cooking up for you too, as long as you can hold out for a few more years.
More »
9:45 AM on Thu Apr 3 2008
By Terry Johnson
1,715 views,
14 comments
Latest by Terry Johnson: Garrison: They are working on tissue engineered pancreas which are basically little sacks of insulin-producing cells. While getting cells to make insulin isn't terribly difficult, modulating the production according to blood sugar levels isn't easy. Bloggy: I wholeheartedly sympathize. Liver's a more »
mad microscopy
The Wellcome Trust, a medical research charity, has just announced the winners of its 2008 imaging contest. Above is my favorite, a picture of a microscopic blood vessel that has ruptured. You can see single red blood cells slowly leaking out. This was taken by Anne Weston, with a scanning electron micrograph. She says the rupture "is due to a mutation in the ephrin-B2 gene that causes the blood vessels to be more fragile than normal leading to an increased rate of haemorrhaging . . . This kind of leaky blood vessel is frequently found in tumours and in certain other human diseases. " Below, we've got a couple more of the winners.
More »
When (Microscopic) Blood Vessels Explode
The Wellcome Trust, a medical research charity, has just announced the winners of its 2008 imaging contest. Above is my favorite, a picture of a microscopic blood vessel that has ruptured. You can see single red blood cells slowly leaking out. This was taken by Anne Weston, with a scanning electron micrograph. She says the rupture "is due to a mutation in the ephrin-B2 gene that causes the blood vessels to be more fragile than normal leading to an increased rate of haemorrhaging . . . This kind of leaky blood vessel is frequently found in tumours and in certain other human diseases. " Below, we've got a couple more of the winners.
More »
science porn
Top Medical Discovery of 2007 Explained via Cartoon
For a long time, it seemed as if a medical discovery that Science called "one of the greatest of 2007" might never get covered by the mainstream media because it was just too complicated. But then an enterprising journalist and artist with the Philadelphia Inquirer boldly went where no reporters dared go. Writer Tom Avril and artist Cynthia Greer figured out how to simplify this complicated discovery into a completely-accurate cartoon (pictured). More »
pharmaceuticals
Provigil is the Cocaine of the Twenty-First Century
Provigil (AKA modafinil) has been called a wonder drug: it can keep you awake and alert for hours without side-effects, and it's even recommended as "the professor's little helper" by neuroscience researchers writing in the prestigious journal Nature. Provigil, approved by the US food and drug administration for the treatment of narcolepsy, is often prescribed "off label" for ailments like severe jet lag, ADHD, and even problems with sleep cycles. But this drug, which is supposed to be a non-addictive stimulant because it doesn't get you high, turns out to be potentially as euphoria-inducing and addictive as cocaine. More »
neuroscience
A New Street Drug That Boosts Your Brain's Ability to Get High
It turns out the gateway drug for amphetamine addiction is a substance provided by your own brain. The culprit protein is called DAT, so named because it is a dopamine transporter — and dopamine is the feel-good, get-motivated neurotransmitter that keeps you happy, hungry, and full of energy. Just as some people are born with the ability to grow larger muscle mass than others, some are born with the ability to squirt more dopamine into their brains because they have a greater-than-average helping of DAT. People with elevated DAT levels are quite literally better at getting high than people with average levels. How do we know? A group of researchers in North Carolina and Pennsylvania recently bred a group of mice to have DAT levels three times above normal and then gave them speed. Here's what happened. More »
to-do lists for futurists
20 Things You Can Put on Your To-Do List Now to Change the World in 100 Years
To-do lists are a great way to plan your week, and it turns out they're also not a bad tool for futurists either. We've put together 20 to-do list items that anyone can use to stop environmental disaster, speed the invention of artificial intelligence, jumpstart a moon colony, and help everyone become posthuman. Usually it seems like ordinary people can't contribute to massive projects that require scientific minds as well as philosophers and other specialists. But there are actually a lot of things you can do. Over the past week we've posted four separate to-do lists for futurists, and now we bring them all together so you can print them out, tuck them in your pocket, and start checking items off to change the world. More »
to-do lists for futurists
This Time Next Year, You Could Be Posthuman
Pundits from Bill McKibben to Susan Greenfield have written scare manifestos about the horrors of a posthuman future where everybody has souped-up DNA and can change their sexes like changing clothes. But here at io9, we are all about the posthuman future: we want to download data directly into our brains, grow a new set of arms (and then take them off again), get cybernetic implants that let us feel electro-magnetic fields, and house nano-colonies in our guts that keep us cancer-free. Plus, we want to have emotional relationships with robots that go beyond hurling our cell phones across the room and crooning to our spastic Linux boxes. If you want to be posthuman too, or transhuman or cyborgian, you'll be waiting a long time. But we've got five things you can put on your to-do list today to make all of us more posthuman by this time next year. More »
biomimetics
This mind-bendingly cute thorny devil lizard is one of the most sought-after creatures in the engineering world because it has a special talent: drinking through its foot. Using cracks in its scales, this little guy can wick water up through its foot into its body. Materials scientists hope that by studying how the lizard does this, they can invent substances that absorb water in a similar fashion. And bioengineers might go further.
More »
This Lizard Drinks Through Its Foot, and Soon You Will Too
This mind-bendingly cute thorny devil lizard is one of the most sought-after creatures in the engineering world because it has a special talent: drinking through its foot. Using cracks in its scales, this little guy can wick water up through its foot into its body. Materials scientists hope that by studying how the lizard does this, they can invent substances that absorb water in a similar fashion. And bioengineers might go further.
More »
mad science
Grow Stem Cells with Shrinky-Dinks and a Pipette
Shrinky Dinks, the plastic toy that shrinks when you expose it to oven heat, has become the preferred material for lab equipment at Michelle Khine's University of California Merced biology lab. Taking the spirit of DiY life sciences into the realm of the pragmatic, Khine previously used Shrinky Dinks to make microfluidic devices. Now she's shrinking the clear sheets of plastic down to make tiny breeding grounds for stem cells — you can see some of the cells hanging out in the shrinky dink above. Check out a how-to video, below. More »
found footage
