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Sat Dec 19
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i'm no nurologist but isn't there a rather large degree of difference between actual alzheimers and 'an alzheimers like state?' i guess what i'm asking is, given that you wouldn't ordinarly given someone whos organs are failing new organs without treating the underlying disease first, why wouldn't the transplanted never cells just succomb to alzheimers themselves? i mean it's a protien folding disease and the 'bad' protiens are still there right?
@aubreyf: Are you implying Artificial Cheese Food Product is not the same as Cheese?!? ^_^
Yeah, good call. Whatever is causing the nerve loss in the first place isn't going to be fixed by adding new cells. It might improve the person's condition short term, but the new cells would more than likely succumb to the same fate as the old ones.
Sadly I can imagine them sending people in for "routine implantation" of nerve cells in order to maintain functionality. This of course would be a great money machine, as it treats the effect and not the cause. Of course one has to wonder if the treatment would even take in an alzheimers patient... or if the disease would block the new cells from integrating in the first place.
@Akitsu: This research seems to be looking at exactly the question of whether such a treatment would take in Alzheimer's patients, and suggests that it would work at the least for some useful duration. Given that the cells apparently came from different source rats, they might or might not succumb eventually.
If it is only a temporary fix? Then, no, it's not as good a solution as curing the underlying condition. But it's better than the no-solution-whatsoever we had previously. Needing regular treatment (say, every six months) sucks compared to being cured forever, but it does beat having your brain turn to swiss cheese. And if we do find a way to fix the underlying condition, it'll still be useful to have a way to reverse any initial damage that occurred before the disease was discovered.
Plus, this research doesn't claim to be the final word. It's a good first step, is all.
@Ghost_in_the_Machine: That would make a nice arc for sweeps. He gets fixed & is evil, but in the end elects to let someone re-insert the crayon in his brain. Let's say, mmm...
Mo.
@John Hazard: I wouldn't be surprised if there is a story arc like this. Of course Walter will reverse the procedure in the end so he can be a good father to Peter. Apparently you can't be an evil genius and a good parent at the same time.
I never understood what's so great about this book. Yes, it touches am important subject, but I knew exactly what was going to happen in this book after the first 20-40 pages. There wasn't a single plot development that surprised me.
As for Will Smith - is name does nothing for my complete disinterest for this film. #flowersforalgernon
Your age when you read it would have a lot to do with that. Before this book was released, there had never been anything like it. Now just about every TV show copies it just like they copy the Mirror Mirror from Star Trek so its lost its impact. #flowersforalgernon
@Jim Topoleski: I don't know that age even matters. When I first read it about 10 years ago or so, I'd already known the ending from other media and I still enjoyed it. #flowersforalgernon
@Jim Topoleski: anywhere between 12 and 15. I've read some sci-fi at that point, not a lot of sci-fi television though. It wasn't that it was too similiar to something I've already known, just a bit too smooth and predictable. I did quite enjoy it, it just wasn't as great as I was told it'd be.
Seems strange that this is the one sci-fi book everybody read despite prejudices against genre. #flowersforalgernon
@lucife: Honestly, while Flowers For Algernon is enjoyed by a lot of people, the book is part of a whole crop of late 1950s literature that started experimenting with form in somewhat strange ways. Algernon is a good book. It is an even better book because of its organization and where it fell in history. Now, my point, not all of us like gimmicks in our writing. Epistolary writing more-often-than-not bothers me, but the characters in Algernon make up for it. Don't feel bad about not liking it. I barely can finish Dracula because of the damn epistles. #flowersforalgernon
Pajiba (which is an awesome site, by the way) occasionally likes to float false rumors to see if other people will believe them. If you're not sure it's true, better corroborate. #flowersforalgernon
@lava: Movie in '68. Cliff Robertson won his Oscar for it.
Watched it in 7th grade for class after we read the short story and I remember it coming off as dated but kind of cool. I should really re-watch it. #flowersforalgernon
It would never have occurred to me to cast Will Smith in an adaptation of FLOWERS FOR ALGERNON... but once I warmed to the idea, I can totally see him in this role. Seriously. #flowersforalgernon
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And how did that spammer get in here?
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I'm not ready to go without Discworld yet! And I'm sure Terry Pratchett isn't either.
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Also what are "never cells" and what happens when you inject them into your brain? :P
12/17/09
Yeah, good call. Whatever is causing the nerve loss in the first place isn't going to be fixed by adding new cells. It might improve the person's condition short term, but the new cells would more than likely succumb to the same fate as the old ones.
Sadly I can imagine them sending people in for "routine implantation" of nerve cells in order to maintain functionality. This of course would be a great money machine, as it treats the effect and not the cause. Of course one has to wonder if the treatment would even take in an alzheimers patient... or if the disease would block the new cells from integrating in the first place.
12/17/09
And if something like this did require routine maintenance how can the patient be expected to remember to do that?
12/18/09
If it is only a temporary fix? Then, no, it's not as good a solution as curing the underlying condition. But it's better than the no-solution-whatsoever we had previously. Needing regular treatment (say, every six months) sucks compared to being cured forever, but it does beat having your brain turn to swiss cheese. And if we do find a way to fix the underlying condition, it'll still be useful to have a way to reverse any initial damage that occurred before the disease was discovered.
Plus, this research doesn't claim to be the final word. It's a good first step, is all.
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Mo.
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The Brain: The same thing we do every night, Pinky. Try to take, er, I like Cheese...
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As for Will Smith - is name does nothing for my complete disinterest for this film. #flowersforalgernon
11/10/09
Your age when you read it would have a lot to do with that. Before this book was released, there had never been anything like it. Now just about every TV show copies it just like they copy the Mirror Mirror from Star Trek so its lost its impact. #flowersforalgernon
11/10/09
11/10/09
Seems strange that this is the one sci-fi book everybody read despite prejudices against genre. #flowersforalgernon
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Watched it in 7th grade for class after we read the short story and I remember it coming off as dated but kind of cool. I should really re-watch it. #flowersforalgernon
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