<![CDATA[io9: genetic]]> http://tags.lifehacker.com/assets/base/img/thumbs140x140/io9.com.png <![CDATA[io9: genetic]]> http://io9.com/tag/genetic http://io9.com/tag/genetic <![CDATA[Mass Extinctions Rise Among Plant Species]]> Entire species of plants are dying off in droves, just like mammals. And there's no way to save them all, say scientists. How do you decide which plant species to preserve at all costs, and which ones to consign to oblivion forever? Answering that question may mean the difference between selective extinction for some — and worldwide extinction for all.

A team from UC Santa Barbara is working on this very question, and they've just published a study in the Proceedings of the National Academy of Sciences. They believe Earth is in its sixth mass extinction, which will kill off nearly 50% of all plant and animal species. Figuring out which endangered plants to save may be the key to minimizing the ecological impact of this particular extinction:

"Losing a very unique species may be worse than losing one with a close relative in the community," said [co-author Todd] Oakley. "The more evolutionary history that is represented in a plant community, the more productive it is."

[Post-doctoral fellow Marc W.] Cadotte explained that the buttercup is a very unique species, evolutionarily. Losing the buttercup, where it occurs in grasslands, would have a much bigger impact on the system than losing a daisy or a sunflower, for example. The latter species are closely related. Each could therefore help fill the niche of the other, if one were to be lost. The daisy and sunflower also have a more similar genetic make-up.

It may be a sad day for the daisy, but ensuring the survival of a genetically diverse array of plant life will help ensure a sufficient level of biomass, and could reduce the devastation a mass extinction would cause.

Image by Martin Heigan.

Current Mass Extinction Spurs Major Study of Which Plants to Save [via Science Blog]

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<![CDATA[Volunteers Let Their Genomes All Hang Out]]> The idea of making personal genetic information public evokes images of genomic Google searches and gene-testing job interviews straight out of Gattaca. But there are many who believe genetic openness could go a long way toward advancing disease research. Tomorrow, ten volunteers will take the first steps away from genetic privacy, allowing their personal genetic information to be posted online without the veil of anonymity.

The volunteers are all participating in the Personal Genome Project, a Harvard study, which as we’ve mentioned before, is attempting to create a database of 100,000 human genomes. Although other services collect genomes as well, PGP has come to public attention for taking personal information in lieu of payment:

In exchange for the decoding of their DNA, participants agree to make it available to all — along with photographs, their disease histories, allergies, medications, ethnic backgrounds and a trove of other traits, called phenotypes, from food preferences to television viewing habits.

So what has prompted these volunteers to make so much of their personal lives publically available? Each possesses, in PGP head George Church’s estimation, the equivalent of at least a master’s degree in genetics, and many have an academic and/or financial interest in furthering genetic research:

• George Church, PhD, Professor of Genetics at Harvard Medical School, Professor of Health Sciences & Technology at Harvard and MIT, and head of PGP.
• Esther Dyson, technology entrepreneur and commentator, philanthropist, and future space tourist.
• Misha Angrist, PhD, Science Editor at the Duke University Institute for Genome Sciences & Policy and author of The Genome Revolution: DNA, Health and Society.
• Keith Batchelder, MD, founder and CEO of Genomic Healthcare Strategies.
• Rosalynn Gill, PhD, founder and Chief Science Officer of Sciona.
• John Halamka, MD, MS, Chief Information Officer of the CareGroup Health System and Chief Information Officer and Dean for Technology at Harvard Medical School.
• Stanley Lapidus, Chairman and CEO of Helicos BioSciences Corp.
• Kirk Maxey, MD, manages the Donor Sibling Registry and the Cayman Biomedical Research Institute.
• James Sherley, MD, PhD, Senior Scientist at the Boston Biomedical Research Institute.
• Steven Pinker, PhD, Johnstone Family Professor of Psychology at Harvard University.

While the “PGP 10” understand the benefits and consequences of posting this sort of information online, some fear that those who follow their lead won’t be so savvy:

“I’m concerned that this could make it seem easy and cool to put your information out there when there is still a lot of stigma associated with certain genetic traits,” said Kathy Hudson, director of the Genetics and Public Policy Center at Johns Hopkins University. “There will be new uses of this data that people can’t anticipate — and they can’t do anything to get it back.”

But some have already been lured in by PGP’s promise of a free genetic screening, which could tell them if they are predisposed toward certain diseases. In the latest issue of GQ, University of Illinois professor Richard Powers shares his own journey through PGP’s gene mapping process, including his decision to join the genetic database and what the geneticists found.

[Personal Genome Project]
Taking a Peek at the Experts’ Genetic Secrets [NY Times]
The Book of Me [GQ]

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<![CDATA["Repo! The Genetic Opera" is an Epic of After-Market Body Parts]]> Darren Lynn Bousman's Repo! The Genetic Opera is one of the two organ repossession movies coming out this year, and now it's gone viral with a creepy-looking donation poster (jump below see it) urging you to give until it hurts. This "Warnerian-Rocky Horror-meets-Bladerunner musical" takes place in a future where massive organ failures plague humankind. But the sickly masses can ward off death by financing an easy-clone organ implant from GeneCo. If you can't pay when the loan comes due, a repo agent will yank your fancy new organs like a bad tooth. And it's an opera, of course. We've got the awesome repo poster below.

RepoOperaposter.jpgHow did a movie like this get made? Bousman, who also directed Saw II through IV, first made a ten minute "trailer" of the stage production of Repo! in order to try to sell it as a film. These are the comic book-style opening titles that tell you what you're in store for. Hopefully the Hollywood executives he's just given the finished film to will see fit to unleash it on theaters.

New 'Repo!' Art
[Bloody Disgusting]

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<![CDATA[An Underwater City Gone Wrong]]> This concept artwork from 2K Games' BioShock shows one of the most starkly dystopian video game worlds created in the past several years. Here you can see one of the observation areas in a city that has seen better days.

There's a central statue of Atlas holding up the world, which has been smashed by a piece of the city falling from overhead. In the background you can see untended plants growing out of control while water pours in from overhead. Meanwhile schools of fish drift lazily by in the background. It's a fully-realized vision of a utopia gone wrong, and we highly recommend getting inside the game and exploring it.

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<![CDATA[What Mutant Powers Are Most Popular?]]> NBC's phenom hit Heroes, the X-Men comic books, and the USA scifi series The 4400 all feature heroic mutants. These super-powered humans have been born with "mutant genes," or they've had some tinkering at the genetic level. But we still see the same powers cropping up again and again. Since the X-Men were first published in 1963, they've got the jump on the two television shows. Are Heroes and The 4400 just ripping off their powers? Let's find out with a look at five mutant abilities that these stories share.

  • Telekinesis.jpgTelekinesis: This power is the most common among the three. While the X-Men had "Marvel Girl" Jean Grey who could move things just by thinking about them, The 4400 have Richard Tyler and his mega-powered daughter Isabelle, both of whom share telekinesis. Of course, the first ability that Sylar ever took from anyone on Heroes was also telekinesss, which he put to extreme use by opening up people's brain cavities.
  • Healing.jpgHealing: Woverine's enviable healing ability has spawned numerous knockoffs, including both Claire and Takezo Kensei on Heroes. On The 4400, Shawn can't heal himself, but he does have the ability to heal others, and in a clever twist he can reverse this ability and injure others as well. While it doesn't have the instant pizazz that Wolverine and Claire get when they grow their own face back, it's a nice adaptation of that ability.
  • Telepathy.jpgTelepathy: The ability to read minds and project thoughts has long been a mainstay in the X-Men books, and The 4400 seem to have most of their powers stem from the mind. Last year police officer Matt Parkman on Heroes was the only person who could read minds, but this season he seems to be able to project his thoughts outwards to others as well. Isabelle on The 4400 is something of a wunderkind among the 4400, and counts telepathy as just one of her many abilities.
  • Precognition.jpgPrecognition: The ability to tell the future always seems to be popular, but it also always seems to come with a price. On Heroes, Isaac Mendez could paint visions of the future, but he couldn't escape his own death at Sylar's hand, which he had painted previously. The 4400's young Maia can see visions of the future, which she records in diaries. This is similar to the X-Men character called Destiny who also recorded her visions in diaries. Although she is now dead, her diaries were one of the main plot points of the 2001 — 2004 series "Xtreme X-Men."
  • Illusions.jpgCreating illusions: Creating illusions and different realities for people happens in the X-Men with Psylocke, Candice does it on Heroes (until Sylar bashes her head in) as does Matt's father, and Alana on The 4400shares this trait. Matt's father can actually trap people in that reality, leaving their body in a comatose state, making him particularly nasty.
  • Until Claire pops some claws out of her hands, or Isabelle starts calling herself Marvel Girl, we'll consider them more as loving tributes instead of a direct knockoff. Although The 4400 needs to stir things up a bit and start handing out some alternate powers. Heroes has them beat in that area, with new powers popping up every week. Of course, with Heroes' "Volume Two" wrapping up very soon, we'll see who survives the cut.

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