<![CDATA[io9: mad science]]> http://tags.lifehacker.com/assets/base/img/thumbs140x140/io9.com.png <![CDATA[io9: mad science]]> http://io9.com/tag/madscience http://io9.com/tag/madscience <![CDATA[Solving The Mysteries Of Cancer Fighting Parasites]]> Could a Chinese fungus provide a crucial missing link to new cancer treatments? Scientists have struggled for decades with one major drawback of the Cordyceps, a parasitic mushroom — but now they may have cracked the riddle.

Cordyceps are parasitic mushrooms grow that on insects-often caterpillars-attack the host and replace its tissue. In some cases, the mushroom alters the behavior of the host, so that when the body dies, the spores can easily spread.

Cordyceps are used in traditional Chinese medicine, and has been investigated in western medicine since the 50s. The problem? They degrade too quickly in the body, limiting their effectiveness. Drugs gathered from coryceps were shown to inhibit the growth and division of cells at low doses — and at high doses, the drug stops cells from sticking together, both invaluable effects to help prevent the spread of cancers.

Now, researchers at Nottingham University have discovered a way to pair Cordycepin with other drugs to substantially increase its lifespan in the body. That gives us the opportunity to understand which cancer types it will target effectively, and how to create other drugs that function similarly.

[via Biotechnology and Biological Sciences Research Council]

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<![CDATA[Real-Life Synthehol Will Get You Buzzed, But Never Drunk]]> In the chronologically later Star Trek series, Starfleet officers rarely worried about overindulging thanks to synthehol, a substance that mimicked alcohol's effects without the drunkeness and hangovers. Now a team of researchers are working to make synthehol a reality.

Researchers at Imperial College London are working to create an alcohol-like drug that would let imbibers experience a pleasant state of inebriation without worrying about becoming drunk, hungover, or physically addicted to the substance. Led by controversial neuropsychopharmacologist David Nutt, the team is looking at benzodiazepines — such as the main ingredient in Valium — to achieve the desired effect. Nutt envisions a world where drinking is safer, with fewer of the accidents and incidents currently related to alcohol.

The advantages of benzodiazepines, according to Nutt, is that they don't affect the brain's addiction centers in the way alcohol does and that they can be easily purged from the body with an antidote. Effectively, if Nutt's research pans out, he claims that drinkers would be able to "switch off" the effects of the faux alcohol by ingesting a pill.

Nutt and his fellow researchers are currently trying to find the benzodiazepine that most closely mimics the effects of alcohol. However, he is concerned that — even if he is successful — European governments will refuse to permit the sale of benzodiazeprine "alcohol," since benzos don't enjoy the same privileged history that alcohol does.

Alcohol substitute that avoids drunkenness and hangovers in development [Telegraph via reddit]

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<![CDATA[The Oceans Are Getting Louder]]> We all know carbon emissions are making our planet warmer. But the increase in carbon brings with it other surprising problems. More carbon apparently means low sounds travel farther underwater, making the ocean a noisier place to live and work.

The reason is complex. Increased atmospheric carbon dioxide also means increased absorption of carbon in the Earth's oceans. And this increase, in turn, means more acidic sea water. More acidic oceans mean less absorption of sound at low frequencies.

And less sound absorption means louder noises over longer distances. In a paper published in Nature Geoscience, scientists predict that, within 100 years, absorption of sounds at around 200 Hz will go down by 70%, meaning sound could travel much farther.

The effects of less absorption and more noise at this frequency could be huge. For instance, scientists and commercial shipping vessels use these lower range frequencies for navigation and oceanic research. Also, marine mammals, such as whales, use these low frequencies for finding food and mates. Noisier oceans might cripple ocean navigation and interfere with whale life.

Unfortunately, the acidification of the ocean won't end when we stop polluting. In fact, the acidic shallow waters will propagate into the deeper ocean, where sound travels farthest, and possibly spread this noisy effect much farther than expected.

Recently, scientists found that blue whale songs are changing, drifting lower in pitch. Their research hinted at the deep complexity of marine life and the in-progress nature of this kind of science. This new marine acoustics research puts an additional wrinkle in the world of underwater communication, making the story more complex and even more interesting.

Man-made carbon dioxide affects ocean acoustics [EurekAlert]

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<![CDATA[Glitter-Sized Solar Cells For Electricity-Producing Clothes]]> While it may look like some sort of metallic snowstorm, this is actually an assortment of tiny photovoltaic cells, each less than a millimeter across. And these minuscule cells could be the versatile, flexible future of solar power.

The cells themselves, created at Sandia National Laboratories, are built using microelectronic and microelectromechanical processes, the same ones used for many of the smallest (and coolest) new microscopic machines.

As with any new and exciting technology, applications seem limitless. The current generation of photovoltaic cells are wafers around 6 square inches. In contrast, these tiny cells could be mounted on flexible substrates, such as on fabric or oddly shaped surfaces.

As an added bonus, the mass-produced micro-cells will also eventually be cheaper to make and install than current solar power cells. This could finally pave the way for buildings that pay their own energy costs with solar power. Or it could mean charging your iPod on the go from a solar-power-collecting shirt.

Glitter-sized solar photovoltaics produce competitive results [PhysOrg]

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<![CDATA[Will The Recession Scar You For Life? Economists Say Yes.]]> People who grew up during the Great Depression often turned into compulsive penny-pinchers, unable to spend money without anxiety. Will recent recessions leave similar psychological scars on people growing up today? A new study by economists suggests they will.

The Boston Globe's Christopher Shea has a terrific discussion of the study on the Brainiac blog:

Giuliano and Spilimbergo made use of the General Social Survey, which has recorded political attitudes among the American public since 1972. The specific questions Giuliano and Spilimbergo explored were whether living through a recession in one's "impressionable years"—defined as 18 to 25—influenced Americans' views on the merits of economic redistribution; on whether financial success resulted largely from hard work or from luck; and on faith in public institutions. Attitudes were analyzed by region, to account for geographical discrepancies in American economic performance. And, because so many people have lived through at least one year of a recession, the study focused on the worst recessions: those in which GDP growth was -3.8 percent for at least one year.

In each case, a recession during one's impressionable years had a significant effect on political and economic attitudes. People with such an experience were more committed to redistribution, more inclined to attribute success to luck, and less likely to trust public institutions. In each case, having been through a severe recession accounted for 4 percent of the variation in attitudes. For the sake of comparison, in the case of income redistribution, that's about one-third of the effect of possessing a high school education—as opposed to a B.A. or B.S, the authors said. (People with college degrees are less amenable to income redistribution.)

Shea points out that if this study turns out to be correct, we can expect the generation coming of age in the next 10 years may have a more "European" attitude toward inequality.

What's heartening about this study is that it shows people who have suffered through hard times often come out wanting to help other people. Hence their commitment to "redistribution," whether through social spending, universal health care, or other programs aimed at redistributing wealth. Unfortunately, a side-effect of recession experiences is that people stop believing in the very public institutions that might - if reformed - be able to help with this redistribution.

via Boston Globe's Brainiac

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<![CDATA[Female Ducks Have Evolved A Vagina Dentata]]> Duck sex is far more interesting than it has any right to be, due to the twisted nature of the birds' genitals. Male and female ducks have corkscrew-shaped sex organs which spiral in different directions. Now we know why.

Ducks are known for their bizarre penises, stretching up to 20cm in size in an anti-clockwise spiral. That's an impressive organ for a bird often only 60cm long. The females, on the other hand, have vaginas that spiral clockwise, opposite to their menfolk. Ducks also engage in what is politely termed "forced copulation", where the male ducks attempt non-consensual sex with the female, and explosively extend their penises with a technique that takes less than half a second.

Eversion in air: from blogs.discovermagazine.com/loom from Carl Zimmer on Vimeo.

This forceful mating is something the females try to avoid. Luckily, evolution is on their side. Female ducks have evolved vaginas that spiral clockwise, and contain sharp turns, which scientists believe were used to prevent insemination by unwanted suitors. This theory has finally been tested by enterprising researchers at Yale, with too much time and glassware on their hands. With sets of cylindrical glass tubes shaped into clockwise or anti-clockwise spirals, they tested how easily the penis advanced through various vaginal configurations. The clockwise vaginas managed to stop the intruding organ, protecting the female duck form unwanted advances.

In fact, the majority of forced copulations don't result in fertilization, and it appears the two sexes are involved in an arms race over their genitalia, with males evolving new attacks and the females defences. The twisted vaginas can completely stop the penis from its explosive exertion, preventing unwanted genes from being passed on. This helps stop undesired advances, and lets females retain control over who will reproduce successfully with them.

It may not be a vagina dentata, but it's a close approximation.

[via Yale]

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<![CDATA[Color-Changing Contacts Monitor Your Glucose Levels]]> For diabetics, finger pricking could be a thing of the past. A biochemical engineer has developed contact lenses embedded with nanoparticles that react with the glucose in tears. As glucose levels change, so does the color of the lens. [PopSci]

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<![CDATA[Chimps Demonstrate Sophisticated Understanding Of Fire]]> The line between human and monkey has been crossed again - this time by chimps. Based on new research, scientists say chimps understand how fire will behave, and move to avoid it "expertly" in the wild.

Primatologist Jill Pruetz from Iowa State University in Ames was studying chimps in Senegal, on the savannahs. It was summer, during brushfire season, and she noticed that the chimps showed no fear of the wildfires at all. In fact, they moved to avoid it easily, predicting where to stand next to avoid the 10-foot flames. She speculates that these chimps were demonstrating a key insight that could lead to controlling fire: "An understanding of the behavior of fire under various conditions that enables one to predict its movement, permitting activity in close proximity to it."

Pruetz told LiveScience:

I was surprised at how expert they were at handling the fire. The fire was burning really hot, and the flames were at least 10 feet high, up to 20 feet at times.

She added that the chimps could predict the fire's next moves better than she could:

I could predict it, sort of, but if it were just me, I would have left. At one time, I actually had to push through them because I could feel the heat from the fire that was on the side of me and I just wasn't that comfortable with it.

The primatologist believes that chimps would have to develop two other key ideas before lighting any fires, however: "The ability to control fire by containing it, providing or depriving it of fuel and perhaps extinguishing it. [And] the capability to start a fire." Once chimps master the next two steps, it's just a slippery slope down to Charlton Heston shaking his fist in Planet of the Apes.

via LiveScience

Photo via AFP

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<![CDATA[Discovery of 4.4-Million-Year-Old Hominid "Ardi" Is Greatest Scientific Breakthrough of 2009]]> Venerable journal Science has announced its top breakthroughs of 2009, and topping the list is a breakthrough in evolutionary biology. It's the discovery of Ardipithecus ramidus, a 4.4-million-year-old hominid skeleton that reveals how homo sapiens' ancient ancestors looked and lived.

According to Science editor Bruce Alberts:

[The Ardipithecus research] changes the way we think about early human evolution, and it represents the culmination of 15 years of painstaking, highly collaborative research by 47 scientists of diverse expertise from nine nations, who carefully analyzed 150,000 specimens of fossilized animals and plants.

Nicknamed Ardi, the hominid lived in what is now Ethioipa, and is a million years older than Lucy, the ancient hominid sometimes called the "missing link" between apes and humans. In fact, there is likely no one "missing link," and instead scientists have discovered there are many stages between proto-humans and what we would recognize as homo sapiens today.

Indeed, a release about the discovery explains:

After analyzing the skull, teeth, pelvis, hands, feet, and other bones, they determined that Ardipithecus possessed a mix of "primitive" traits, shared with its predecessors-the apes of the Miocene epoch-and "derived" traits, which it shared exclusively with later hominids. However, many of its traits do not appear in modern-day African apes. One surprising conclusion, therefore, is that it is likely that the African apes have evolved extensively since we shared that last common ancestor, which thus makes living chimpanzees and gorillas poor models for the last common ancestor and for understanding our own evolution since that time.

In other words, humans did not evolve from apes at all. Present-day apes and humans are radically different from their common ancestor.

Other breakthroughs this year, according to Science, included:

Pulsars Detected by Fermi: NASA's Fermi Gamma-Ray Space Telescope helped to identify previously unknown pulsars-highly magnetized and rapidly rotating neutron stars-and shed light onto their unique gamma-ray emissions.

Rapamycin: Researchers found that tinkering with a key signaling pathway produces life-extending benefits in mice-the first such result ever achieved in mammals. The discovery was particularly remarkable because the treatment did not start until the mice were middle-aged.

Graphene: In a string of rapid-fire advances, materials scientists probed the properties of graphene-highly conductive sheets of carbon atoms-and started fashioning the material into experimental electronic devices.

Plant ABA Receptors: Solving the structure of a critical molecule that helps plants survive during droughts may help scientists design new ways to protect crops against prolonged dry periods, potentially improving crop yields worldwide and aiding biofuel production on marginal lands.

LCLS at SLAC: SLAC National Accelerator Laboratory unveiled the world's first x-ray laser, a powerful research tool capable of taking snapshots of chemical reactions in progress, altering the electronic structures of materials, and myriad other experiments spanning a wide range of scientific fields.

Gene Therapy Comeback: European and U.S. researchers made progress in treating a fatal brain disease, inherited blindness, and a severe immune disorder by developing new strategies involving gene therapy.

Monopoles: In an experimental coup, physicists working with strange crystalline materials called spin ices created magnetic ripples that model the predicted behavior of "magnetic monopoles," or fundamental particles with only one magnetic pole.

LCROSS Finds Water on the Moon: In October, sensors aboard a NASA spacecraft detected water vapor and ice in the debris from a spent rocket stage that researchers deliberately crashed near the south pole of the Moon.

Hubble Repair: In May, a nearly flawless final repair mission by space-shuttle astronauts gave the Hubble Space Telescope sharper vision and a new lease on life, resulting in its most spectacular images yet.

via Science

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<![CDATA[Transplanted Rat Brains Could Beat Alzheimer's]]> Transplanting small numbers of nerve cells directly into the brain has restored the learning ability of brain-damaged rats — and might be able to defeat the memory loss of Alzheimer's disease.

Scientists in India have been researching transplanting parts of the nervous system in order to help sufferers of Alzheimer's Disease. By replicating the disease's effects in rats, they've found that transplanting nerve-cells brings back the animals' ability to learn.

The researchers at India's National Institute for Mental Health and Neuro Sciences and National Centre for Biological Sciences first damaged the subiculum of the rats brain, which lead to the deterioration of the hippocampus. The shrinkage of the hippocampus during Alzheimer's disease is thought to lead to the loss of memory and learning, the most visible of disease's effects.

Once the rats had been brought to this Alzheimers-like state, the researchers took cultured lines of hippocampal cells — taken from newborn transgenic rats and cultured — and precisely injected them into the hippocampi of half the rodents. After two months, both batches of rats were run through standardized mazes. The rats that had received the injections were back to pre-damage levels of learning and recall, while those that hadn't received the transplants struggled to learn the course.

What seems to have happened is that the transplanted cells settled in an area of the hippocampus called the dentate gyrus, where they proceeded to help pump out growth factors which create an environment were neurons can grow. There was a threefold increase in neurotrophic and fibroblastic growth factor, which allowed the hippocampus to regenerate from the inflicted damage, and restored the rat's abilities to learn and remember to the level of un-damaged rats.

The implications of this research are astounding for sufferers of neurodegenerative diseases. This study is specifically designed as a precursor to further work with Alzheimer's, but altering the brain to create an environment where it can succeed in regenerating damaged components is a fascinating concept. These seedling transplants could revolutionize the way we look at repairing the brain, for a disease that effects millions.

[via APA, presented in Behavioral Neuroscience; image of rat hippocampus via University of Texas]

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<![CDATA[We Can Replace Your Blood Cells With Synthetics]]> A few years from now, your blood transfusion may contain synthetic blood cells (pictured) almost indistinguishable from the real thing. Except in one important way: These synth-cells can be stuffed with drugs for special delivery via your circulatory system.

A team of California researchers discovered that they could create blood cells by layering hemoglobin and other proteins on top of a microscopic, donut-shaped polymer mold. When the proteins had a stable structure, they removed the polymer mold and presto - they had a classic blood-cell shaped hollow vessel. The cells are also biodegradable, so you wouldn't have synth-cells roaming your body forever. Here are typical red blood cells, below.

One synth-cell could carry oxygen through the blood just like a typical red blood cell, its unique shape allowing it to squeeze through tiny capillaries. But it could also carry drugs like anti-coagulant heparin, releasing it gradually. This could prove a boon for doctors trying to administer drugs to highly-targeted areas fed by the circulatory system. And of course it could prove a perfect system for hiding data or other sensitive substances in your bloodstream. One injection of synth-cells and you're carrying secret plans around in your blood that can't be detected by anyone.

via PNAS

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<![CDATA[Accidental Supervillain on Trial for Causing Earthquakes]]> Markus Haering probably didn't intend to emulate Lex Luthor when his company's drilling triggered a series of minor earthquakes. But the geothermal energy mogul is up on criminal charges for his earth-shaking exploits.

In 2006, Haering's company was drilling in Basel, Switzerland, as part of a project to convert heat in the underground rocks into electricity. But Swiss authorities charge that the drilling activated the major fault line that runs underneath the city, triggering a series of small earthquakes. Although the most intense of these quakes only rated a 3.4 on the Richter Scale and resulted in no injuries, the Swiss government claims Haering's drilling caused $9 million worth of property damage. Furthermore, they claim there is a 15 percent chance that, had the drilling continued, it would have triggered a major quake that could have caused $500 million in damage.

If Haering is found guilty of deliberately triggering the quakes, he could be jailed for up to five years. But this wouldn't be the first time human actions led to shaky ground. Wired lists five ways humans can cause earthquakes of their very own, including examples of a handful of other accidental Lex Luthors.

Switzerland geologist on trial for 'causing quakes' [BBC via Slashdot]

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<![CDATA[Octopus Uses Coconut Shells as Portable Armor]]> Tools aren't just for vertebrates anymore. The veined octopus has been spotted lugging around coconut shells to serve as mobile shelters, the first time scientists have observed tool use in an invertebrate species.

Humans living on the Indonesian coast frequently discard halved coconut shells in the ocean, and it turns out that their eight-legged neighbors have been making use of them. Researchers have filmed veined octopi, Amphioctopus marginatus, moving the shell halves by placing their bodies inside the hollowed-out portion, draping their legs over the edges, and bringing the shells along for the ride. When the coconut-carrying octopus feels threatened, it will pull the half shell over its body (or sometimes pulls two halves of a whole coconut over itself), and wait inside their armored home until the threat passes.

Veined octopi have been seen hiding out inside coconut shells before, but researchers hadn't realized that the creatures were deliberately carting the shells around for this purpose. Marine biologist Julian Finn of Melbourne's Museum Victoria caught a lucky glimpse of a veined octopus carrying and using the shells, and has since filmed four octopi doing the same thing.

Finn and other researchers argue that this is the first reported use of tools by an invertebrate species, as this is a sophisticated, costly behavior in which an animal manipulates an object for future plans. While others argue that it does not fit the standard definition of tool use, since the octopus isn't using the object to act on another object, it may still require a sophisticated level of cognition, and we should investigate what makes such foresight possible.


Octopuses use coconut shells as portable shelters [New Scientist]

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<![CDATA[A Device That Lets You Type With Your Mind]]> By placing electrode grids inside patients' skulls, researchers at the Mayo Clinic have created a way for people to type words using only their brainwaves. It's a major breakthrough for brain-computer interface research.

The experiments were undertaken on patients who already had electrodes in their brain to monitor epilepsy. Readings were taken via electrocorticography (ECoG), as the subjects were shown a grid of letters and numbers. As each symbol was illuminated, the patient was told to focus on the letter or number, and data was recorded. Once this calibration data was taken, the patients would think of a letter or number, and their brain waves would be appropriately translated to the screen. The theory is that this technique will allow people to communicate and type far more easily when they suffer from Lou Gehrig's disease, MS, or paralysis.

The lead scientist on the project, Dr. Jerry Shih, says the program is able to perform near or at 100% accuracy for the patients. While this isn't far from the results from studies using non-invasive EEG, Shih believes that ECoG has advantages, as the scalp and skull distort the information coming from the brain, which means that ECoG has potential to be faster and more accurate. Shih also said that with EEG, "the accuracy isn't terribly great, and it takes a long time for the computer system to learn an individual's brain signals and to correctly interpret."

It is early days yet, and there are still numerous hurdles for the research. The initial study was only with two patients, but they're now on to the sixth, with plans for a wider study, to ensure that this technique is universally applicable. Shih's system does require a craniotomy, which is not a surgery to be taken on a whim; and an interpreter device is required, which must be tuned to an individual user. There is also the fact that EEG based interfaces don't require the invasive surgery, and are similarly accurate, even if they are slower and not quite as precise. So in terms of market adoption, the implant is at a disadvantage. Most people would be willing to deal with the speed loss to avoid dangerous procedures.

Shih is currently working on ensuring the method's effectiveness. He believes it could be used for controlling prosthetics as well as typing. It could also possibly be trained with images instead of letters. Imagine an item, and an image or word for it would appear on your screen.

The device could be available in as little as 5-10 years.

It's just a matter of time before this technology filters down from medical to elective, and we can all live out our cyberpunk dreams of plugging our brains directly into a computer.

Via American Epilepsy Society and Mayo Clinic

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<![CDATA[Talk Monkey to Me: Monkey Language Contains Simple Sentences]]> While other primates have exhibited simple vocabularies, it has long been believed that syntax, the construction of sentences, was unique to humans. But a recent study suggests that at least one species of monkey communicates in vocalized sentences.

A research team led by Klaus Zuberbühler of the University of St. Andrews has been studying the calls of the Campbell's monkey, a primate found in the Ivory Coast. The team looked at how the calls of adult male monkeys vary in response to various stimuli. Campbell's monkeys have six different types of individual calls, each of which has a distinct meaning. What's surprising, however, is that these monkeys actually string together multiple types of calls to create communications with entirely new meanings. Zuberbühler and his team claim this is a form of syntax, suggesting that Campbell's monkeys have developed a sort of sentence structure. Other primates, such as chimpanzees, have shown an understanding of language, able to connect words and symbols with specific meanings, but haven't been able to combine those words into sentences.

The team has identified the meanings of the individual calls, as well as how they can be combined to form completely different communications:

The "boom-boom" call invites other monkeys to come toward the male making the sound. Two booms can be combined with a series of "krak-oos," with a meaning entirely different to that of either of its components. "Boom boom krak-oo krak-oo krak-oo" is the monkey's version of "Timber!" - it warns of falling trees.

Combining the "boom-booms" and "krak-oos" with a third sound, "hok-oo," warns monkeys of the presence of other monkey groups. It appears that initially, the monkeys developed the calls to warn each other of specific predators, such as leopards and eagles, but their anti-predator vocabulary has evolved into something much more sophisticated.

Boom! Hok! A Monkey Language Is Deciphered [NY Times]

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<![CDATA[Charting the Possible Evolution of Same-Sex Liaisons]]> Same-sex sexual behavior has evolved multiple times in various animals, including mammals, birds, fish, and even insects. Researchers are increasingly finding that the reasons such behaviors evolved are as varied as the animals themselves.

The always excellent New Scientist has an article synthesizing much of the research into same-sex sexual behavior in animals and the possible evolutionary explanations. They spoke with University of California evolutionary biologists Marlene Zuk and Nathan Bailey, who recently published a paper examining same-sex behavior in various species. Zuk and Bailey note that same-sex sexual behavior in other animals can't necessarily be equated with sexual orientation in humans, researchers have come up with similar questions as to why certain animals have evolved to include members who expend energy on same-sex liaisons.

Evolutionary biologists have come up with various hypotheses for why same-sex behavior has evolved in various animals. In some cases, same-sex behavior has emerged as a result of specific adaptations, such as to foster social bonding, or because certain genes for same-sex attraction hold another survival benefit when only one copy is present. In some cases, though, the behavior is incidental, such as in certain fish that cannot easily tell male and female members apart.

Below, New Scientist charts several of the possible evolutionary explanations for same-sex sexual behavior in various species:

Bailey believes that exploring the evolution of sexual behavior will give us a better understanding of evolution, including the development of our own species:

"Given its persistence in species in many different animal groups, including humans, viewing it as an evolutionary force in its own right promises to provide a much richer understanding of the evolution of reproductive behaviour," Bailey says. He suggests we could make some fascinating comparisons. Might male-male copulation in species as diverse as flour beetles and dolphins have similar, even predictable, evolutionary consequences? More daringly, could understanding the evolutionary consequences of same-sex interactions in animals help us understand our own evolution?

Homosexual selection: The power of same-sex liaisons [New Scientist]

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<![CDATA[Could New Therapies For Drug-Resistant Staph Help To Breed Even Worse Mutant Super-Bacteria?]]> Antibiotic-resistant staph bugs are a terrifying prospect: a potentially deadly skin infection that resists most traditional treatments. But now, researchers think they've found a weapon against MRSA: hitting it with low-temperature plasma.

One set of researchers from the Max Planck Institute for Extraterrestrial Physics are trialling a device for quickly disinfecting human skin using low-temperature plasma, which would save a significant amount of time, compared to traditional hospital scrubbing.

The second is an "argon plasma torch", developed with ADTEC Plasma Technology Ltd in Japan, for disinfecting chronic non-healing wounds. This terrifying sounding device can specifically target bacteria but is harmless to human cells.

MRSA (Methicillin-resistant Staphylococcus aureus) arose as such a threat because it is mutation that is resistant all but the most powerful antibiotics. It can prove lethal if it spreads to your heart or other key organs. But finding stronger treatments against MRSA may not be the best long-term solution — by attacking the bugs with plasma, we may ensure that the mutations that survive will be even tougher. We're effectively breeding Fremen bacteria.

[via the Institute of Physics]

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<![CDATA[Give Me A Biotech Apocalypse That I Can Believe In]]> So Hollywood trashed the world in 2012, and scourged it in The Road. But neither apocalypse delivered the sweet tang of satisfaction. That's because what the Earth needs now are life-distorting biotech mutation stories. Here's why.

First of all, there haven't been very many biotech apocalypse flicks at all, even though genetic engineering and other genome/proteome-based weirdness are freaking everybody out in the pop science media. Possibly 28 Days Later is the iconic example of a biotech apocalypse, since it's a human-made virus that unleashes the zombie hoardes. But honestly, we can do better than plagues - we've all seen those before. Besides, the upcoming World War Z movie is probably going to hold the whole plague subgenre hostage to its awesomeness next year.

So what would have to happen to produce a really great biotech apocalypse that wasn't just a virus scare with zombies that made us all think disappointedly of I Am Legend?

First of all, the biotech armageddon would have to affect the entire biosphere, not just humans. When it comes to imagining this scenario I always think of Kathleen Ann Goonan's Jazz Quintet novels, which begin with Queen City Jazz. She creates a future where many people move into biotech cities whose entire infrastructure is mutable and organic - genetically-engineered bees keep the cities "growing" by fertilizing the buildings, which are actually giant wildflowers. The problem comes when the city itself is infested with a virus that causes its entire fabric to remake itself to resemble stories from files stored in the city's library. What if your city decided that it wanted to be a film noir Paris, and then reprogrammed every person and building to emulate that (fictional) place?

If you wanted to go even weirder, visit the scenarios that Rudy Rucker comes up with in Hylozoic, where every object on the planet becomes sentient. Suddenly you are having an emotional relationship with your telephone, which has a lot of opinions about how you've abused it in the past.

I'm not saying we need movie versions of these books, though that might be nice if done by the right people. What we need is for mainstream media to catch up to what is happening in literature and in the lab.

Though I wasn't entirely crazy about Minority Report, one thing that film got right was its emphasis on believable technology. The filmmakers went to MIT, checked out labs where futuristic computer interfaces and biotech are being invented, and incorporated them into the film. I'd love to see the movie that got made after some filmmakers spent some time hanging out at the Department of Energy's Genome Research Institute, or the Max Planck Institute in Europe - or, hell, how about just reading even one essay by Drew Endy? In fact, you don't have to read - you can just watch him talk about synthetic biology here:

If researchers can genetically-engineer bacteria whose behavior changes with a flash of light, or build poplars that contain termite genes so that they break down into ethanol more easily, imagine what kind of apocalypse we're facing. That's right - it's not necessarily an apocalypse at all. It's simply a world packed with flora and fauna we couldn't possibly recognize today. In her novels Oryx and Crake and Year of the Flood, Margaret Atwood imagines that this will result in creepy half-human pigs and sheep who sprout human hair that can be sold as wigs. There is something admittedly horrifying about the idea that humanity could reshape the biosphere in its greedy, simian image. What marks the biotech apocalypse is that it's a scenario where life as we know it doesn't end - it turns into new forms of life.

What I'm saying is that I want to see stories where synthetic biology generates cities and technologies like the ones Jeff VanderMeer imagined in his recent novel Finch, where spore people grow buildings and guns from mushrooms. And I want these tales to do what few apocalyptic tales have dared to do: Explore what it means when what has been destroyed isn't the world, but instead just one instance of the world.

One of the most basic truths we learn from evolutionary theory and geology is that the world we live in - the one whose climate and landmasses we fuss about endlessly - is in fact just one version of Earth. For a long period, Earth had a different set of gasses in its atmosphere, and all life lived in the seas. The composition of our biosphere and state of our climate has changed dramatically over the millennia. C'mon Hollywood - give us a story where the world doesn't suffer apocalyptic death, but instead a dramatic rebirth. One that begins in our nanoscopic genomes, not in mega-explosions.

Image via Yanko Design

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<![CDATA[Luke Skywalker's Robotic Hand Comes Even Closer to Reality]]> Are we coming upon the era of bionic limbs? Another company has created a robotic hand that can be controlled by the wearer's thoughts and restores tactile sensation — and the subject claims it feels almost like a real hand.

An Italian research team, lead by neurologist Paolo Maria Rossini, created the LifeHand, the latest in a long line of robotic prostheses. The team performed microsurgery to attach the hand 26-year-old Pierpaolo Petruzziello, who lost much of his left hand in a car accident. Petruzziello apparently mastered the hand in just a few days, and it responded to 95 percent of his mental commands. He claims that he also received incredible sensory feedback from the hand, even registering needle pinpricks.

Several weeks ago, another team reported successful experiments with an artificial hand that provided sensory feedback, but the LifeHand team claims that the experiments with Petruzziello represent the first time a subject has made achieved such complex movements with a prosthetic using only their mind. It's also the longest a subject has worn such a prosthetic; Petruzziello wore the LifeHand for a month. More research is needed, however, before a prosthetic can be tested long-term.

Perhaps the most impressive aspect of the LifeHand is that it didn't require Petruzziello to learn any new neurological tricks. He simply sends the same sorts of signals to the robotic hand as he sends his right hand, and gets nearly the same result.


The bionic hand controlled by thoughts [Sun via DVICE]

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<![CDATA[The Mystery of Titan's Methane Lakes - Solved?]]>
Saturn's atmosphere-shrouded moon Titan is dotted with methane lakes, giving it a geography like Saskatchewan or the Great Lakes region in the US. But why are all the lakes grouped in the northern hemisphere of the moon?

Scientists at Caltech think they may have uncovered the reasons for Titan's extremely odd lake arrangement. Data gathered by the Cassini orbiter showed 20 times more area in the Northern extremities were covered by liquid ethane and methane, when compared to the South. The researchers, headed by Oded Aharonson, think that the transport of methane northwards may be due to the elliptical orbit of Saturn, and hence Titan.

Over the course of one Titan year (29.5 Earth years), the Northern hemisphere summer is long and mild, but the Southern hemisphere version is short and intense. That's because in the Southern summer season Titan is around 12% closer to the sun. While this doesn't make a huge difference over the course of a year, it does over a longer time period: It's possible that these uneven seasons result in methane evaporating in the south, drifting northward in the clouds, and then raining prodigiously in the milder north.

Around 32,000 years ago, the situation would have been reversed, with the hydrocarbons traveling Southward instead of North.

This theory is being published in this month's Nature Geoscience. Other possible explanations for the lakes include the idea that there is some (as yet unknown) fundamental difference between the hemispheres. It's also possible the methane transfer happens every season, not gradually.

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