<![CDATA[io9: Neuroscience]]> http://cache.gawker.com/assets/base/img/thumbs140x140/io9.com.png <![CDATA[io9: Neuroscience]]> http://io9.com/tag/neuroscience http://io9.com/tag/neuroscience <![CDATA[Why Dyslexics Are Good Computer Programmers]]> dyslexickid.jpg People suffering from dyslexia may find that their problems evaporate when they learn a new language, especially one that works with symbols very different from their native one. A study released yesterday reveals that brain abnormalities in English-speakers with dyslexia are quite different from those in people who speak Chinese. So it's very possible that a person who is dyslexic in Chinese wouldn't be in English, and vice versa. This also helps explain why so many dyslexics are able to excel at computer programming, which requires them to write very precisely in a computer language.

According to Discovery News:

Dyslexia affects different parts of children's brains depending on whether they are raised reading English or Chinese. . . "This finding was very surprising to us. We had not ever thought that dyslexics' brains are different for children who read in English and Chinese," said lead author Li-Hai Tan, a professor of linguistics and brain and cognitive sciences at the University of Hong Kong. "Our finding yields neurobiological clues to the cause of dyslexia."
Why would English and Chinese dyslexia be different? Continues the article:
Reading an alphabetic language like English requires different skills than reading Chinese, which relies less on sound representation, instead using symbols to represent words . . . For children, learning to read is culturally important but is not really natural, Eden said, so when the brain orients toward a different writing system it copes with it differently. For example, English-speaking children learn the sounds of letters and how to combine them into words, while Chinese youngsters memorize hundreds of symbols which represent words.
The researchers suggest language-specific therapies for dyslexia which account for these differences: English-speaking dyslexics would learn to read by focusing on sounds. Chinese-speakers would focus more on memory cues.

However, another possibility is that English-speakers with dyslexia might be better-suited to read and write in Chinese. And vice-versa. Teaching children both languages could be another way to foster writing ability and reading comprehension. Image via Discovery.

Dyslexia Differs by Language [Discovery News]

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http://io9.com/377561/why-dyslexics-are-good-computer-programmers http://io9.com/377561/why-dyslexics-are-good-computer-programmers Tue, 08 Apr 2008 16:04:28 PDT Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=377561&view=rss&microfeed=true
<![CDATA[Stick Your Severed Spine Back Together with a New Biochemical Gel]]> Severed spines may not mean paralysis for much longer. Inject a special gel into mice with severed spinal cords and six weeks later the mice are back on their feet. It's a pretty neat trick, one that scientists at Northwestern accomplish by impregnating the gel with biochemical signals that hinder the growth of scar tissue and promote growth of myelin, the sheath that protects nerve cells and fosters their growth.

John Kessler, lead author on the Journal of Neuroscience paper says it'll be at least a few years before you find the gel in your local hospital, and it hasn't been shown to work in humans yet. He plans to submit the gel to the Food and Drug Administration for approval as a pharmaceutical in the not-too-distant future.

Source: Northwestern University via EurekAlert

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http://io9.com/376151/stick-your-severed-spine-back-together-with-a-new-biochemical-gel http://io9.com/376151/stick-your-severed-spine-back-together-with-a-new-biochemical-gel Fri, 04 Apr 2008 13:20:00 PDT Michael Reilly http://io9.com/index.php?op=postcommentfeed&postId=376151&view=rss&microfeed=true
<![CDATA[Ultrathin, Rubbery Circuits Bring Us One Step Closer to Google Brain Implants]]> brainimplant.jpg A new kind of computer circuit printed on ultrathin rubber would make the perfect "brain wrapper," says its inventor. Usually computer circuits are etched on rigid, plastic boards, but University of Illinois researcher John Rogers has successfully placed circuits on a rubbery material that can bend and stretch. Many groups have been working on developing this technology, but Rogers is the first to demonstrate that his bendy circuits actually work. Rogers says the circuits could wrap around part or all of the brain, to monitor its electrical activity. Or — in future applications — to interface with your brain, perhaps using antennae to establish a wireless neural link to the internet so you can be Googling with your mind.

Says Rogers:

We'd like to have an electric circuit that could wrap around part of the brain and detect signal patterns to predict the onset of seizure before it happens . . . You can't take a sheet of plastic and wrap a brain, you really need stretchability.
For now, though, Rogers is focusing on just making the circuits work. He makes them by stretching a thin, rubbery material to 15 percent of its normal size, binds the circuits to it, and then snaps it back to its normal size. The circuits continue to work, and can also work if re-stretched or bent. Here's a video of how that looks under a microscope.

Another possible application for the technology is skintight, wearable computers. Sort of like PVC for the BSD set. Image via USA Today.

Stretchy Circuits
[New Scientist]

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http://io9.com/373180/ultrathin-rubbery-circuits-bring-us-one-step-closer-to-google-brain-implants http://io9.com/373180/ultrathin-rubbery-circuits-bring-us-one-step-closer-to-google-brain-implants Thu, 27 Mar 2008 17:00:00 PDT Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=373180&view=rss&microfeed=true
<![CDATA[A New Street Drug That Boosts Your Brain's Ability to Get High]]> neuronsDATaddict.jpg It turns out the gateway drug for amphetamine addiction is a substance provided by your own brain. The culprit protein is called DAT, so named because it is a dopamine transporter — and dopamine is the feel-good, get-motivated neurotransmitter that keeps you happy, hungry, and full of energy. Just as some people are born with the ability to grow larger muscle mass than others, some are born with the ability to squirt more dopamine into their brains because they have a greater-than-average helping of DAT. People with elevated DAT levels are quite literally better at getting high than people with average levels. How do we know? A group of researchers in North Carolina and Pennsylvania recently bred a group of mice to have DAT levels three times above normal and then gave them speed. Here's what happened.

According to the Proceedings of the National Academy of Sciences:

Ali Salahpour and colleagues explored the impact of DAT levels on the response to amphetamines—a group of addictive chemicals closely tied with dopamine sensitivity. Amphetamines are used legally to treat ADHD, narcolepsy, and to suppress appetite, but are well-known as illicit "club" drugs and performance enhancers. To investigate the consequence of high DAT levels, the researchers developed transgenic mice with three-fold higher levels of DAT compared with unmodified animals. The authors discovered that the drug was more powerful in animals with more DAT. The dopamine-enhanced animals were more sensitive to the effects of amphetamines, becoming hyperactive and more rewarded by the drug, according to the authors.
Tinkering with DAT levels is something that researchers are already trying in order to deal with things like hyperactivity and depression. Now it seems there might be a street value for DAT-enhancers. Take a hit of DAT, snort a line of speed, and you'll get more bang for your buck. Image via Paul De Koninck.

Increased Amphetamine-Induced Hyperactivity [PNAS]

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http://io9.com/371649/a-new-street-drug-that-boosts-your-brains-ability-to-get-high http://io9.com/371649/a-new-street-drug-that-boosts-your-brains-ability-to-get-high Mon, 24 Mar 2008 17:00:11 PDT Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=371649&view=rss&microfeed=true
<![CDATA[Rewire the Neurons in Your Brain Just By Looking]]> eyeanatomy.jpg Though science fiction tales like Clockwork Orange and Videodrome have toyed with the notion that images from television and movies could rewire people's brains, the idea has always been controversial and unsubstantiated. But now researchers have shown empirically that anything you look at, including movies, changes the the connections between neurons in your brain. In other words, what you see changes your brain at a neurological level. The good news is the parts of your brain devoted to vision can be rewired, which has positive implications for people blinded after strokes. The bad news is that what you see today could have a lasting effect on what you see tomorrow. A particularly powerful negative image might alter your perception of positive images later.

According to a release:

In the study, [Valentin] Dragoi and co-author Diego Gutnisky, a graduate research assistant at The University of Texas Graduate School of Biomedical Sciences at Houston, measured the effects of visual stimulation on the responses of multiple neurons whose electrical activity was measured simultaneously in animals. They carefully examined the responses of a population of cells in visual cortex to dynamic stimuli, which consisted of movie sequences displayed on a video monitor.

"We provide empirical evidence that brief exposure, or adaptation, to a fixed stimulus causes pronounced changes in the degree of cooperation between individual neurons and an improvement in the efficiency with which the population of cells encodes information," Dragoi and Gutnisky report. "These results are consistent with the 'efficient coding hypothesis' - that is, sensory neurons are adapted to the statistical properties of the stimuli that they are exposed to and with changes in human discrimination performance after adaptation." . . .

While their study focused on how neuronal populations adapt to visual stimulation, the same could hold true for other senses - hearing, smell, taste and touch, Dragoi said. "We're trying to understand how a network of sensory neurons changes its encoding properties to properly represent the environment," he said. "Our results may have general implications for sensory and motor coding in a variety of brain areas."

What's truly interesting about this study is that images from film seem to remold our brains as much as real-world ones. So if people watch a lot of violent movies, it's actually possible that the neural links formed as a result will influence what they see in reality. Note that this doesn't mean it would make people more violent — it might just make them perceive violence more readily, or might cause them to interpret things as being more violent than they are. Image via LinMercer.

First Empirical Study Demonstrating that Populations of Nerve Cells Adapt to Changing Images [Eurekalert]

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http://io9.com/367165/rewire-the-neurons-in-your-brain-just-by-looking http://io9.com/367165/rewire-the-neurons-in-your-brain-just-by-looking Wed, 12 Mar 2008 16:10:57 PDT Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=367165&view=rss&microfeed=true
<![CDATA[Rejuivenate Your Brain with Umbilical Cord Blood]]> neurogenesis.jpg As brains age, they slowly lose the ability to generate new neurons, which results in a diminishing ability to learn new things and retain memories. But today a group of neuroscientists in Florida announced a strange cure for what amounts to brain decay: blood from the umbilical cords of human infants. When the researchers injected this blood into aging rats, it kickstarted a new round of neurogenesis in their brains, helping them to grow new neurons and shed some other effects of brain aging. Essentially, effects of aging were rolled back. There's tremendous potential here for helping aging humans to regain the plasticity of their youthful minds.

A release about the study explained:

Co-author Alison Willing, PhD, of the USF Center of Excellence for Aging and Brain Repair [said,] "The increase in neurogenesis we saw after injecting UCBCs seemed to be due to a decrease in inflammation."

According to lead author Carmelina Gemma, Ph.D., of the James A. Haley Veterans Administration Medical Center (VA) and USF, the decrease in neurogenesis that accompanies aging is a result of the decrease in proliferation of stem cells, not the loss of cells.

"In the brain, there are two stem cell pools, one of which resides in the hippocampus," explained graduate student and first author Adam Bachstetter. "As in other stem cell pools, the stem cells in the brain lose their capacity to generate new cells. A potent stressor of stem cell proliferation is inflammation."

Prior to this study, the research team led by Paula C. Bickford, Ph.D., of the VA and USF found that reducing neuroinflammation in aged rats by blocking the synthesis of the pro-inflammatory cytokine IL1B rescued some of the age-related decrease in neurogenesis and improved cognitive function.

"We think that UCBCs may have a similar potential to reduce inflammation and to restore some of the lost capacity of stem/progenitor cells to proliferate and differentiate into neurons," said Dr. Bickford.

It's almost as wild as that time in Battlestar Galactica when President Roslin's cancer went into remission after she got injected with Cylon blood. Except it's real. Image from Braincells Inc.

Umbilical Cord Blood Stimulates Neurogenesis [BMC Neuroscience]

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http://io9.com/366156/rejuivenate-your-brain-with-umbilical-cord-blood http://io9.com/366156/rejuivenate-your-brain-with-umbilical-cord-blood Mon, 10 Mar 2008 16:17:14 PDT Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=366156&view=rss&microfeed=true
<![CDATA[A Robot That Does Brain Surgery Guided by MRI]]> Most precision brain surgery is done with robotic assistance, but there's one place robots can't go: inside MRI brain scanners. Enter the neuroArm, a robot specially designed to work inside the powerful magnet of an MRI — and guided by the detailed images the MRI creates. Developed by surgeons and robotics experts at University of Calgary, the neuroArm combines the best of telepresence surgery with the best imaging technology. But how do you create a sophisticated robot, with delicate actuators, that can withstand being destroyed by a giant magnet? We've got the answer, and cool videos of the arm in action, below.

neuroArm2.jpg Here's an artist's rendering of a person undergoing brain surgery inside an MRI machine. Now surgeons can guide the robotic arms with even more precision, seeing exactly where each surgical tool goes as it enters your gray matter. So what is the robotic arm made of? Check out what the roboticists and surgeons who built it have to say in this video. And here's another picture of neuroArm, the brain surgery robot. Yup, it's just plain cool. neuroarmAP1.jpg Images via AP.


Project neuroArm
[University of Calgary]

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http://io9.com/361188/a-robot-that-does-brain-surgery-guided-by-mri http://io9.com/361188/a-robot-that-does-brain-surgery-guided-by-mri Wed, 27 Feb 2008 07:00:15 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=361188&view=rss&microfeed=true
<![CDATA[A "Reset Button" for the Brain Could Cure Alzheimers]]> With a little help, our brains can be trained to heal themselves. After a traumatic brain injury, some of your brain cells go into reset mode, reverting to a stem cell-like state. Using these "reset cells," a group of German researchers were able to coax the brains of injured mice to regrow neurons to replace damaged tissue (the images above are micrographs of the cells regrowing over time).

Though their methods are far from perfect, this breakthrough could help replace dead or damaged brain cells in people suffering from Alzheimer's as well as any type of injury. It's just a matter of extending the brain's natural self-healing powers.

According to an article in the Proceedings of the National Academies of Science today:

Magdalena Götz and colleagues found that cells called astrocytes expand and multiply after brain injury. The authors induced brain injury in mice, then observed as quiescent astrocytes activated themselves and became reactive, causing reactive gliosis, which is the universal cellular reaction to brain injury. The researchers found that the reactive astrocytes remained astrocytes in the cerebral cortex, whereas in a cell culture they could be coaxed to switch to different brain cell types, including neurons. These results identify astrocytes as a source of stem cells in the injury site and show that other types of brain cells do not have this potential. The authors conclude that the cells provide a promising cell type to initiate repair in humans after brain injury.
A source of multipotent cells in the injured brain [PNAS] ]]>
http://io9.com/361112/a-reset-button-for-the-brain-could-cure-alzheimers http://io9.com/361112/a-reset-button-for-the-brain-could-cure-alzheimers Tue, 26 Feb 2008 15:00:12 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=361112&view=rss&microfeed=true
<![CDATA[The Pros and Cons of a Google Brain Implant]]> In John Varley's upcoming scifi novel Rolling Thunder, everyone has a brain implant that lets them google information constantly. And many futurists are saying this technology will become a reality long before we colonize Mars. The question isn't whether we'll have google brain implants (or the futuristic search engine equivalent), but how we'll handle them. What exactly would be the plusses and minuses of being able to google information instantaneously in your head, without anybody knowing you're doing it?

A google brain implant could work in lots of ways. With technology we have right now, people could wear a brain-computer interface helmet like the one sold by Emotiv, and use that to control the cursor on a wearable computer with a tiny monitor that's attached to your classes. So the thing wouldn't be implanted in your brain, but it would be responding to electrical signals from your brain. More sophisticated wearables like those described in Vernor Vinge's novel Rainbows End might allow you to google via subtle movements of your body, and then display results in special contact lenses.

A more far-future implant might actually have a direct neural linkup to your brain, allowing you to see google results on your retina. No matter how the instant, subtle, brain-controlled access to google works, the same benefits and problems are likely to exist.

PRO:

Ability to "remember" many details about a person or issue in the middle of a conversation, so that you can marshal facts quickly and check the accuracy of what other people are saying.

CON:

The person you're talking to could much more easily pretend to be somebody they are not by googling information and feigning expertise.

PRO:

You will never get lost because you've got maps at your synapse tips, and you'll always know what's playing at your local theaters. You'll also get the latest news headlines and stock quotes at the twitch of an eyelid.

CON:

You'll spend so much time in your head reading google news and watching YouTube that you'll zone out during conversations and forget to pay attention to what your best friends are telling you (unless they're telling you in the form of a google news alert).

PRO:

Instant access to infinite data storage allows you to quickly store your every interesting thought, and search through them instantly. More innovative ideas result.

CON:

Over reliance on "offloaded" memory means people make less of an effort to remember important things and therefore brain flexibility actually erodes. Ideas become boring repetitions of what you've thought up before, or what other people have thought up and posted on the Web.

PRO:

You can cheat on tests.

CON:

You can cheat on tests.

PRO: Need something desperately and can't get to the computer to order it? Just buy it through Froogle.

CON: Google ads are constantly running in your head, perhaps designed to respond to thought patterns.

PRO: Every time Google ads a cool new service, like Gmail or Picasa, you've got instant access to it in your brain.

CON: Google is famous for its "silent update" system, which occasionally results in pretty buggy services. Imagine what it will be like when Google silently updates your brain.

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http://io9.com/359932/the-pros-and-cons-of-a-google-brain-implant http://io9.com/359932/the-pros-and-cons-of-a-google-brain-implant Fri, 22 Feb 2008 17:30:58 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=359932&view=rss&microfeed=true
<![CDATA[Manipulating a Single Protein in Your Brain Creates "Autistic Savants"]]> Some autistics are known as "autistic savants" because they develop a genius in one subject, such as mathematics or art. New research shows this syndrome can be induced by tinkering with one protein in the brain which is responsible for building synapses, the brain structures that help neurons talk to each other. Neuroscientists at MIT (pictured) bred rats that lacked this protein, known as Shank1, and discovered the creatures could do spacial learning an extremely rapid clip, though they showed other signs of severe autism. These neuroscientists' work could go in two directions: curing some kinds of autism, and inducing selective superintelligence.

According to Albert Y. Hung, a staff neurologist at Mass General and co-author of the study:

These opposite effects on different types of learning are reminiscent of the mixed features of autistic patients, who may be disabled in some cognitive areas but show enhanced abilities in others. The superior learning ability of these mutant mice in a specific realm is reminiscent of human autistic savants.
MIT news reports:
Hung said that while it seems counter-intuitive that loss of an important synaptic scaffold protein would result in improved learning among the mice in this study, the absence of this protein may "trap" the mice's synapses in a more plastic state, which means the synapses are ready to respond to input but not maintain it in long-term memory. Aberrant synapse development and faulty structure of dendritic spines—tiny protrusions on the surface of neurons that receive messages from other neurons—are often associated with neurodevelopmental disorders, including autism, in humans.
It's possible that if researchers could induce the plasticity of synapses by tinkering with Shank1, they could help people learn more quickly. The trick would be staving off the side-effects, such as the autism spectrum disorders which cause long-term memory problems and emotional fragility. Photo by Donna Coveney.

Gene research may help explain "autistic savants" [MIT News] ]]>
http://io9.com/359230/manipulating-a-single-protein-in-your-brain-creates-autistic-savants http://io9.com/359230/manipulating-a-single-protein-in-your-brain-creates-autistic-savants Thu, 21 Feb 2008 10:20:57 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=359230&view=rss&microfeed=true
<![CDATA[Do Women Predict the Future Differently Than Men Do?]]> Men and women have such different perspectives that many pop psychologists say they must think about the future differently too. But if that's what you believe, new evidence from brain scans done on men and women will shake your faith. Last year, Harvard cognitive scientists Donna Addis and Daniel Schacter asked men and women to do a series of mental exercises while in an fMRI brain scanner. First they had to remember a recent event, and then they had to imagine a future event in great detail. The results of these "mental time travel" experiments were surprising.

It turned out that men and women use exactly the same parts of their brains to engage in the imaginative exercise required to imagine, a future scenario. Even more intriguing was that both genders relied heavily on the Hippocampus, a part of the brain that's usually associated with memory. Write the authors in a study published earlier this year in the journal Hippocampus:

Behavioral, lesion and neuroimaging evidence show striking commonalities between remembering past events and imagining future events. In a recent event-related fMRI study, we instructed participants to construct a past or future event in response to a cue. Once an event was in mind, participants made a button press, then generated details (elaboration) and rated them. The elaboration of past and future events recruited a common neural network.
Another cognitive scientist, Eleanor Maguire from the Wellcome Trust, has done related experiments and confirms that indeed both genders use the exact same parts of their brains to imagine future events. So if you and your opposite-sex pals have different opinions about what should happen tomorrow — or in twenty years — it's not a brain difference. It's just a matter of opinion.

Past and future events modulate hippocampal engagement
[PDF] ]]>
http://io9.com/358380/do-women-predict-the-future-differently-than-men-do http://io9.com/358380/do-women-predict-the-future-differently-than-men-do Tue, 19 Feb 2008 16:20:56 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=358380&view=rss&microfeed=true
<![CDATA[Babies Can Communicate with Numbers Before Talking]]> babymath1.big_0.JPG Human infants are born with an innate mathematical ability that allows them to count large numbers of objects more easily than groups of two or three. A new study of 4.5 month old infants' "number sense" suggests that emphasizing language before numbers is the wrong way to teach kids about the world. Babies can figure out when there's been a change in the number of a large group of objects before they can understand language. Therefore communicating with toddlers via numbers could become the best way to shape young minds.

The study of babies' math skills — which did involve silly EEG hats like the one above — also revealed something more general about human brains. When we look at a group of objects, different parts of our brains process the number of objects and the type of objects. So we recognize how many duckies there are with a different brain region than the one that recognizes that we are looking at duckies.

Says a release about the study:

Behavioral experiments indicate that infants aged 4 ½ months or older possess an early "number sense" that allows them to detect changes in the number of objects. However, the neural basis of this ability was previously unknown. This week in the online journal PLoS Biology, Véronique Izard, Ghislaine Dehaene-Lambertz, and Stanislas Dehaene provide brain imaging evidence showing that very young infants are sensitive to both the number and identity of objects, and these pieces of information are processed by distinct neural pathways.

Distinct Neural Pathways for Object Identity and Number in Young Infants [PLoS Biology]

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http://io9.com/353606/babies-can-communicate-with-numbers-before-talking http://io9.com/353606/babies-can-communicate-with-numbers-before-talking Thu, 07 Feb 2008 07:30:18 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=353606&view=rss&microfeed=true
<![CDATA[Neuroscience Explains Why You Get Pleasure From Hurting Yourself]]> paddle.jpg It turns out there is a neurological explanation for why people scratch and cut themselves, and spank each other for pleasure. Inflicting small amounts of physical pain, whether from scratching your skin vigorously or doing something more extreme, deactivates the parts of your brain associated with unpleasant or painful emotions. Though scientists have long speculated that there was some kind of neurological payoff from self-inflicted pain, a study published yesterday demonstrated precisely why your brain gets a reward when you hurt your body.

The study focused on scratching, which is a common, slightly-painful thing that everybody does to relieve itches. Researchers stuck people in an MRI brain imaging machine and scratched their legs with brushes for five minutes, watching to see which parts of their brains were active or non-active. Areas associated with painful feelings became less active, as well as areas associated with memory. The researchers say:

We know scratching is pleasurable, but we haven't known why. It's possible that scratching may suppress the emotional components of itch and bring about relief.
It's also possible that the pain of scratching, or more intense pain from cutting, suppresses painful memories too.

The researchers suggest that further study might reveal a way to produce a drug that has the same effects as scratching or cutting does on the brain — thus preventing physical damage while providing the same relief.

Ah, that's the spot [Reuters]

Research suggests why scratching is so relieving [Eurekalert]

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http://io9.com/351348/neuroscience-explains-why-you-get-pleasure-from-hurting-yourself http://io9.com/351348/neuroscience-explains-why-you-get-pleasure-from-hurting-yourself Fri, 01 Feb 2008 07:30:49 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=351348&view=rss&microfeed=true
<![CDATA[One Pill Makes You Autistic -- And One Pill Changes You Back]]> Need to finish that work project, and wish you had the mental intensity to do it? Just take a synapse-regulating inhibitor, induce temporary autism, and you'll want to ignore your friends and do nothing but number-crunching for days. Autism-inducers could become as popular as Provigil among the geek set by 2020. Last night, in fact, a group German researchers announced they'd perfected the method for inducing autism. (They can also cure it.)

Over the past year, researchers have demonstrated several times that they can turn mice autistic by messing with brain chemistry — and then "cure" them using the same techniques. The discoveries could lead to a scenario similar to the one in Vernor Vinge's novel A Deepness in the Sky, where people are given a brain treatment called "focusing" that essentially turns them autistic and makes them obsessive, detail-oriented workers.

It might also lead to recreational autism, where people who want to take a break from having messy emotions about other people decide to unplug and enter a state where human relationships are no more important than inanimate objects.

Read about how scientists can induce autism [PNAS] and how they can cure it [BBC News].

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http://io9.com/349956/one-pill-makes-you-autistic-++-and-one-pill-changes-you-back http://io9.com/349956/one-pill-makes-you-autistic-++-and-one-pill-changes-you-back Tue, 29 Jan 2008 07:30:29 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=349956&view=rss&microfeed=true
<![CDATA[A Chemical That Improves Memory (and Cures Loneliness)]]> Social isolation makes people stressed out and forgetful, but soon a drug could cure this problem. Late last year, scientists isolated a brain enzyme that triggers the "loneliness" feelings during periods of solitude. Replenishing that enzyme in the brain could enhance memory and relieve stress when you're spending a lot of time by yourself working (or space traveling).

Researchers at the University of Illinois kept several mice in isolation from each other to see what chemical changes took place in their brains. Turns out the lonely mice experienced reduced levels of a brain enzyme that helps create a stress-relieving neurosteroid called allopregnanolone. A release from the Proceedings of the National Academies of Science, where the researchers' paper was published, explained:

Such alterations in the synthesis of allopregnanolone may account for the anxiety, aggression, and memory impairments that result from social isolation, the authors suggest.
It's possible that boosting the enzyme that helps create allopregnanolone could relieve feelings of loneliness that trigger memory blocks. Or perhaps simply administering allopregnanolone would do it too. Either way, further research might uncover a drug that would make it possible for humans to undergo intensive periods of aloneness without going mad.

Image is of a fluorescent neuron.

Social-isolation behavior in mice [PNAS]

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http://io9.com/347030/a-chemical-that-improves-memory-and-cures-loneliness http://io9.com/347030/a-chemical-that-improves-memory-and-cures-loneliness Mon, 21 Jan 2008 07:30:36 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=347030&view=rss&microfeed=true
<![CDATA[Brain Scans Reveal That Inflation Gets You Hot]]> lustSign.jpg Inflated prices trigger the pleasure centers in your brain more than fair ones. Not only is the idea of buying something expensive more exciting than buying something on sale, but you'll actually get more genuine pleasure out of something expensive — even if it's not worth the cost. A group of social scientists at CalTech and Stanford discovered this not-entirely-unexpected fact when they stuck people into MRI brain scanners and gave them several glasses of wine, assigning each one a random price.

In point of fact, all the wines were exactly the same. But the results of the MRI scans showed greater neurological activity in people's pleasure centers when they were told they were drinking expensive wine. The best (creepiest?) part of all this is that the authors of the study hope to use these findings to manipulate consumers. The authors write:

Our results show that increasing the price of a wine increases subjective reports of flavor pleasantness as well as blood-oxygen-level-dependent activity in medial orbitofrontal cortex, an area that is widely thought to encode for experienced pleasantness during experiential tasks. The paper provides evidence for the ability of marketing actions to modulate neural correlates of experienced pleasantness and for the mechanisms through which the effect operates.
Yes, marketing can modulate your neurological system. You already knew that, but somehow finding out that there's an objective truth to it in a brain scanner makes it feel more like Big Brother than Brooks Brothers.

Marketing actions can modulate neural representations of experienced pleasantness [PNAS]

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http://io9.com/344868/brain-scans-reveal-that-inflation-gets-you-hot http://io9.com/344868/brain-scans-reveal-that-inflation-gets-you-hot Tue, 15 Jan 2008 07:20:42 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=344868&view=rss&microfeed=true
<![CDATA[Regrow Nerves in Your Spine]]> SpineAssist.jpg Getting your spine crushed doesn't have to mean paralysis. In fact, there is new evidence that nerves in the spine can regrow and be rerouted around damaged areas to connect with the brain. According to Discovery News . . .

Experiments conducted on mice at the University of California in Los Angeles showed for the first time that the central nervous system can rewire itself to create small neural pathways between the brain and the nerve cells that control movement.
Mice who suffered damage to their spines, in the experiments, regrew some nerves and regained most of their mobility in 8 weeks. Doctors might work on helping your nerves regrow using a spinal surgery robot like this one (pictured), built by Mazor Surgical Technologies. Tiny Nerves Rewire Themselves in Mice [Discovery News] ]]>
http://io9.com/342334/regrow-nerves-in-your-spine http://io9.com/342334/regrow-nerves-in-your-spine Tue, 08 Jan 2008 11:42:06 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=342334&view=rss&microfeed=true
<![CDATA[Fully-Functioning Synaesthesia Machine]]> You've probably heard about synaesthesia, the glamorous neurological condition in which people's senses get swapped so that they smell colors and feel words. Now a group of roboticists and bioengineers have got a working prototype of a little machine that gives you the synaesthetic ability to feel things you see. This tiny device attaches to your fingertip, using a camera to translate visual images into feelings by activating a little vibrator attached to the sensitive nerves in your finger. So you wave your hands around and "feel" objects across the street.

The creators of this device, called the Fingersight, write:

Extending the hand's innate ability, we mount miniature cameras on individual fingertips, permitting rapid sweeping through the 3D visual environment at greater distances. The information gleaned from each fingertip camera is fed back to that finger by a small vibrator, so the sense of touch remains related to each finger's individual interaction with the environment. Metaphorically speaking, we have given eyesight to the fingers, and thus we call the resulting capability, "Fingersight."
They've been working on this device and demoing it at conferences for about a year. Can't wait for the consumer version. Whoa, man, I can FEEL the colors on that chair across the room. No really, I can.

Fingersight [IEEE Xplore]

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http://io9.com/340282/fully+functioning-synaesthesia-machine http://io9.com/340282/fully+functioning-synaesthesia-machine Thu, 03 Jan 2008 14:40:38 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=340282&view=rss&microfeed=true
<![CDATA[Science Proves That Drinking Makes You Horny]]> jadzia1.jpg You probably already guessed this from observation in the real world, but alcohol makes people hornier and more likely to hit on you cluelessly. Now a team of researchers from Penn State have gotten a bunch of fruit flies drunk on a daily basis to prove that mating behavior skyrockets when you're an alcoholic. And by "mating behavior," I do not mean actual mating. Read on to find out how alcohol gives you wandering crotch syndrome.

Apparently the more you drink, the more your brain's neurological structure gets rewired to crave the drinkies. (This is something that people who study addiction have known for a while.) What nobody knew before was exactly how that re-wired affected sexual behavior. Turns out it causes "disinhibition," which makes flies more likely to try to mate — with anybody:

Among the team's discoveries is that male fruit flies, which typically court females, also actively court males when they are given a daily dose of [alcohol's active ingredient] ethanol.
OK this explains the one frat party I attended in college.

Daily Alcohol Use Causes Changes in Sexual Behavior
[Eurekalert]

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http://io9.com/339908/science-proves-that-drinking-makes-you-horny http://io9.com/339908/science-proves-that-drinking-makes-you-horny Thu, 03 Jan 2008 10:30:22 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=339908&view=rss&microfeed=true
<![CDATA[Scientists Use Your Brain to Read Other People's Minds]]> brainreading.jpg Your private thoughts could be used to pry information out of somebody else's mind. Today a group of neuroscientists announced they used test subjects' brains to train computers how to "recognize" electrical patterns created by thoughts. Specifically, they trained the computers to recognize thoughts about objects such as hammers and drills. You can imagine how this would come in handy during interrogations: Just stick a person in an MRI and scan her brain for telltale patterns while you ask her what kinds of weapons the bad guys have. So, how did the researchers do it?

Scientists conducted an experiment where they asked people in an MRI brain scanner to look at ten pictures of different tools and houses. Meanwhile, the researchers fed the data into a computer algorithm so that the program would learn to recognize the unique signature of electrical patterns produced by the objects in each subject's brain. Eventually the algorithm began to "recognize" thought signatures associated with the objects. The surprise was that people's thought patterns related to each object were quite similar.

Tom Mitchell, a neuroscientist and computer scientist at Carnegie Mellon who worked on the study, said:

There has always been a philosophical conundrum as to whether one person's perception of the color blue is the same as another person's. Now we see that there is a great deal of commonality across different people's brain activity corresponding to familiar tools and dwellings.

Mitchell's co-author Svetlana Shinkareva at University of South Carolina added alarmingly:
We hope to progress to identifying the thoughts associated not just with pictures, but also with words, and eventually sentences.
Remember what I was saying about interrogation? Yeah. Let's hope they don't go there.

Using fMRI Brain Activation to Identify Cognitive States Associated with Perception of Tools and Dwellings [PLoS One]

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http://io9.com/339390/scientists-use-your-brain-to-read-other-peoples-minds http://io9.com/339390/scientists-use-your-brain-to-read-other-peoples-minds Wed, 02 Jan 2008 07:20:08 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=339390&view=rss&microfeed=true
<![CDATA[A Performance-Enhancing Drug for Scientists and Professors]]> jekyll.jpg Barry Bonds isn't the only guy trying to better his game with drugs. If you're trying to compete for the best grants and patents in the cut-throat science industry, you might be taking modafinil (AKA Provigil). Named "professor's little helper" in a Nature commentary today, modafinil is a stimulant that its users compare to a double shot of espresso. The best part? It's totally legal, and is available online. Find out more about it from the experts.

Two neuroscience experts interviewed in Nature, Barbara Sahakian and Sharon Morein-Zamir, talked about mind performance-enhancing drugs for healthy people who aren't suffering from disorders like ADHD or Alzheimers. They say:

In academia, we know that a number of our scientific colleagues in the United States and the United Kingdom already use modafinil to counteract the effects of jetlag, to enhance productivity or mental energy, or to deal with demanding and important intellectual challenges.
Sahakian and Morein-Zamir argue that as long as people are taking performance-enhancing drugs under the care of a doctor, prescriptions should be granted on a case-by-case basis. Soldiers and air-traffic controllers, they say, are obviously prime candidates for performance-enhancers.

And, apparently, so are professors.

Professor's little helper [Nature Commentary]

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http://io9.com/335844/a-performance+enhancing-drug-for-scientists-and-professors http://io9.com/335844/a-performance+enhancing-drug-for-scientists-and-professors Wed, 19 Dec 2007 11:00:59 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=335844&view=rss&microfeed=true
<![CDATA[Hawaii 5-0 Brainwaves Sent to Space, Return Expected in 1,920 Years]]>

Artists these days don't just use paintbrushes and canvas. Spencer Finch, in fact, uses brainwaves, a popular sixties TV show, microwave signals, and the bluest stars in the night sky. Aptly named "Blue (one second brainwave transmitted to the star Rigel)," this piece is actually an early 1990s neuroscience experiment that won't yield results for almost 2,000 years.

While you hunker down in front of the TV screen, which is showing an episode of Hawaii Five-O, the electrodes behind the orange chair read your brainwaves. Then the antenna sends microwave signals containing your brain waves to the bluest star in the sky. The bluest star in the sky, for those of you who don't know, is 960 years away. At least according to Finch's calculations. Let's hope the 'waves get there safely without running into alien ships.

Here's another sky-oriented sculpture by Finch, called Cloud.

cloud.jpg

Images courtesy of Spencer Finch

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http://io9.com/325619/hawaii-5+0-brainwaves-sent-to-space-return-expected-in-1920-years http://io9.com/325619/hawaii-5+0-brainwaves-sent-to-space-return-expected-in-1920-years Wed, 21 Nov 2007 14:00:21 PST LISA KATAYAMA http://io9.com/index.php?op=postcommentfeed&postId=325619&view=rss&microfeed=true
<![CDATA[Welcome to New Brainland]]> Image by Sam Brown [Bioephemera]

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http://io9.com/324223/welcome-to-new-brainland http://io9.com/324223/welcome-to-new-brainland Mon, 19 Nov 2007 06:15:10 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=324223&view=rss&microfeed=true
<![CDATA[An MRI Machine On Every Desktop]]> You'll be taking pictures of your brain while checking email with new, consumer-grade magnetic resonance imaging (MRI) machines developed by an Israeli company called Aspect Technologies. Yesterday the company announced a six million dollar cash infusion from a secret US investor. Usually getting an MRI is very expensive, and can only be done in a hospital, but now Aspect Technologies might make these machines into fancy bio-feedback devices that you could use to see which part of your brain is active when you are stressed — and which parts light up when you have an orgasm.

Just as people who do bio-feedback can train themselves to calm down, you could train yourself to have extra-intense orgasms by learning what it is you're doing when your brain shows the most intense orgasms occurring. Think I'm kidding? Rutgers University professor Barry Komisaruk has suggested that this would be an ideal use for home MRI machines. Not to mention that they can help you locate damage in carpal tunnel syndrome, and figure out exactly where there's blockage in your hands to make the circulation so bad in your fingers. Someday, MRI machines will be as common in the home as thermometers are today. Image by MAURICIO LIMA via Getty.

Portable MRI Technology [Medgadget]

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http://io9.com/321928/an-mri-machine-on-every-desktop http://io9.com/321928/an-mri-machine-on-every-desktop Tue, 13 Nov 2007 07:40:16 PST Annalee Newitz http://io9.com/index.php?op=postcommentfeed&postId=321928&view=rss&microfeed=true