<![CDATA[io9: organs]]> http://tags.lifehacker.com/assets/base/img/thumbs140x140/io9.com.png <![CDATA[io9: organs]]> http://io9.com/tag/organs http://io9.com/tag/organs <![CDATA[More Opera, More Repo Men, and More Guts]]> The website for Repo The Genetic Opera has gone live, which means we must be closer than ever to seeing this film in theaters instead of in dribs and drabs on the interwebs. I've been excited about this movie for a while, partly because it stars Buffy's Anthony Stewart Head as a freakish organ repo-man and partly because it's a bunch of people wearing fetish clothing, singing, and bathing in blood. It's sort of like Doomsday, but with more singing and fewer Scottish people. [Repo the Genetic Opera site via Whedonesque]

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<![CDATA[How Many of Your Internal Organs Can You Live Without?]]> Organ failure is one of those annoying problems many of us face — often sooner than we want to. The good news is that there are a lot of organs you can live without. You probably already know, for example, that your appendix and tonsils can be removed entirely without any harm done. But there are several other organs you can live without, or replace with synthetics, that you didn't know about. Get ready for a body without organs in our helpful guide to five organs you can can get rid of.

heartvalve.jpg 1. Heart valves. We haven't got a replacement for your heart yet — though a lot of people are researching it — but you can replace your heart valves with artificial ones like those manufactured by ATS Medical. These simple-looking device are fitted to your heart, opening and closing with each beat of your heart to push the blood through your body. Without heart valves, your heart has to work much harder to pump and will grow enlarged — generally a condition that leads to death. Many people are born without a heart valve, or lose one in a heart attack. They can also be replaced by heart valves from a dead human or pig.

2. Bladder. Tissue engineers have successfully grown bladders from human bladder cells, then transplanted them back into the patients whose malformed or damaged bladders provided the cell samples. Several people have received these synthetic biological bladders since 2006. They are beta bladders, and the patients aren't always continent. But now they have full-sized bladders when they didn't before, and that dramatically improves quality of life. So you can survive if you lose your bladder — just as long as you've got a few bladder cells left for tissue engineers to grow you a new one.

3. Large intestine. Many people with colitis — an immuno-deficiency disease that causes inflammation and tearing of the colon — have colectomies to remove the entire organ. But that doesn't mean they have to wear a colostomy bag. Surgeons can use a section of the small intestine to create a J-shaped pouch inside your body that acts as a surrogate colon. It's not as big as your large intestine was, so you have to visit the bathroom a bit more often. But you don't have to wear a bag, and you're surviving just fine with no colon at all.

4. Stomach. Like your large intestine, your stomach can be completely removed. Usually this is done when you have stomach cancer. The esophagus (the pipe that routes food from your mouth to your stomach) is rerouted to connect to your small intestine, and the surgeon can widen the small intestine in that area to create a surrogate stomach. Food goes through the same digestive process as before, but you can't absorb as much vitamin B12. So you may have to get bi-annual injections of the vitamin. wearableartificialkidney.jpg 5. Kidneys. You've probably heard about kidney dialysis, where people with kidneys that don't function get stuck in a giant machine that de-toxifies their blood for hours. It's a crappy process, but it does mean that you can live without a kidney. The good news, though, is that there is now a wearable dialysis device, pictured above, which you put on your body like a belt. It doesn't work quite as well as dialysis, but it does the trick and many patients prefer it to the weekly dialysis clinic visit. We've written about the kidney dialysis wearable, and heart valves, before.

Top image "The Food" from artist Jeanne Dunning.

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<![CDATA[A Better Debugger for the Software That Runs Your Cybernetic Heart]]> Semi-permanent heart pumps like this one are installed in people's hearts all over the world. The problem is that when these software-controlled pumps fail, the blue screen of death is literally killing people. So researchers at Frunhofer-Gesellsschaft Research, who make a popular model of heart pump (or VAD, for ventricular assist device), have invented this model which will serve as a debugger. New software will run on this human simulator, and researchers can see what might go wrong before it stops your heart.

Fraunhofer Institute for Computer Architecture researcher Holger Schlingloff, who helped develop the device, says:

It's a similar development to that of the automobile, where a considerable number of functions now rely on software, such as driver assistance systems. At the same time, the technical requirements for vehicle registration have become more demanding: certain models on sale 15 years ago would not be allowed on the road under today's standards. Exactly the same applies to cardiac support systems.
Adds his colleague Rolf Hänisch:
It is impossible to prove that a system is entirely failure-proof by simply running a test - it could be that certain types of fault have been overlooked. We can eliminate this shortcoming by producing systematized tests based on models, in which we record and simulate all relevant test scenarios.
Of course it's still not foolproof, but it's still a good system for testing software that has to work — or else.

Odd side note: Frunhofer-Gesellsschaft is the same company that patented the MP3 algorithm. I want my VAD to play MP3s, please!

Relief for Diseased Hearts [Fraunhofer-Gesellschaft Research via Medgadget]

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<![CDATA[You Can Live Without Heart Valves and Kidneys]]> Two new artificial organs rolled out in the past week are going to make things a hell of a lot easier for people with malfunctioning (or absent) heart valves and kidneys. The first device (pictured) is an artificial heart valve that can replace the part of your heart that pushes blood through your body. Being born without a heart valve (you have two, a right and a left) is a common congenital heart defect. Most people get it repaired with a cadaver valve — the valve from a dead person or a dead pig. Those work great, but are prone to infection. So this artificial valve could save lives. And the wearable artificial kidney is even cooler.

kidney.jpg With this small, wearable device (see photo and diagram), people who suffer from kidney problems might never have to get dialysis again. The machine would do the dialysis for them. kidneydiagram.jpg Kidneys purify our blood, among other things, and so this device would do that job, sucking your blood out, passing it through a purifying filter, and then pumping it back into your body after removing toxic waste and passing that out to an external bag. The device from Xcorporeal is a bit bulky and awkward, but patients say it beats getting hooked up to a dialysis machine for 12 hours a week. Photo via Lancet.

Artificial heart valve and Wearable Artificial Kidney [MedGadget]

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<![CDATA[Body Organs Get Yanked In Clash Of Repo Movies]]> In the future, you'll be able to pay for new organs on credit, just like decorating your home. But what happens when you can't payoff the new body parts you've been enjoying? That's the premise of not one but two new films coming out next year. And one of them is a musical. Only in Hollywood.

In one corner, you have Director Darren Lynn Bousman's independent effort with Lionsgate, Repo! The Genetic Opera. Weighing in on the studio side is Repossession Mambo from Universal. While Repo! stars Paul Sorvino and Paris Hilton, Mambo has Jude Law and Forest Whitaker. Both are about people who pay for body organs on credit, and then find out what happens when they can't pay the bills. So long new set of lungs!

To make things even more bizarre, Bousman blogged that they are sharing post-production facilities with Repossession Mambo. Talk about being able to see what the enemy is up to. He remains steadfast that his film will trump Mambo, and points out they "We really did start this Opera shit!" He seems to have a valid argument as well, since he'd already shot a short version of Repo! in 2006, and used it to pitch the feature to studios. Plus his movie has singing and dancing and... Paris Hilton.

One of these is a dramatic movie, and the other one looks like a Rocky Horror Picture Show for a new generation. We'll let you decide which is which.

Every so often two films come down the pipeline with the same basic plot and smash into each other. Once the dust settles, a winner is declared, and the loser slinks into bargain bins and late-night showings on cable TV. This gave us such memorable box office battles as Armageddon vs. Deep Impact, Volcano vs. Dante's Peak, A Bug's Life vs. Antz, and Transformers vs. Transmorphers.

Repo! vs. Repo Hits The Editing Room [Bloody Disgusting]

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