The Crossover We Never Knew We Wanted: Brainy Smurf Vs. The Brain

It's just a photo of two toys facing off, but this photo by JD Hancock has us imagining all sorts of scenarios in which Brainy and the Brain have to team up. (To take over the world, of course.) » 11/19/14 4:19pm 11/19/14 4:19pm

Stories That Lost Their Writers (And Their Plots) Halfway Through

Sometimes it can be confusing to be a fan of pop culture. Sometimes writers leave halfway through a story, and a new writer has to wrap things up somehow. Sometimes a creator gets fired, and the replacement told to change gears in a hurry. Here are 20 stories that changed drastically when the writer left in the middle. » 9/08/14 1:01pm 9/08/14 1:01pm

Pinky And The Brain Have Finally Reached Their Breaking Point

Everyone has a limit where they just stop refusing to put up with shit. Some people — like the megalomaniacal Animaniacs' character Brain here — will put up with his compatriot Pinky's gross incompetence for years until he snaps... as captured in the above video in all its profane glory. » 7/30/14 7:00pm 7/30/14 7:00pm

The Funniest Star Wars Tributes This Side Of The Galaxy

Tonight, The Big Bang Theory celebrates Star Wars Day with a Star Wars-themed episode. But can it begin to measure up to the wealth of funny Star Wars tributes in television, movies, and comics? » 5/01/14 1:07pm 5/01/14 1:07pm

​A good night of sleep is like hosing down your filthy brain

Why animals sleep remains one of the enduring mysteries of biology, but new research suggests the primary reason might be to allow cerebrospinal fluid to wash all the gunk out from between your brain cells. » 12/30/13 7:20am 12/30/13 7:20am

Nursery School named after Pinky And The Brain is certainly up to no…

The Pinky and the Brain School is a real school that is 100% named after the adorable Animaniacs cartoon duo. Located in the capital city of Nigeria, we can only imagine what the classes are like. But they all should only have one goal — to try to take over the world. » 4/01/13 8:20am 4/01/13 8:20am

Vote for the greatest animated TV theme song of all time

Welcome to the second io9 music smackdown! We're putting together the ultimate science fiction (and fantasy) playlist - all the music that everyone should have on his or her iPod. » 9/02/11 3:40pm 9/02/11 3:40pm