Leaving aside characters with alphanumeric names (like Star Wars' R2-D2 and C-3PO), characters who also have serials number imparted to them by their governments but are not generally addressed as such (as in Nineteen Eighty-Four and The Giver), and characters whose first names happen to mean a number in a different language (as with many of the characters in Stardust and Mobile Suit Gundam), there are several characters who are either designated with or often called by a number:

Number One (Star Trek "The Cage"/"The Menagerie"): More than two decades before Captain Picard started referring to William Riker as "Number One," Majel Barrett filmed the original Star Trek pilot, where her character was known only as Number One. Like Riker, Number One was the Enterprise's first officer, but the novel Vulcan's Glory suggests Number One was her actual name, given to her because she possessed the top intellect of her planet's generation.

Number 5 (Short Circuit): Although roboticists Newton Crosby and Ben Jabituya were out to create artificial intelligence, they probably didn't expect any of their prototypes to suddenly gain sentience, and so assigned them numbers in lieu of names. But after prototype Number 5 becomes self-aware (and escapes the clutched of the US military), he decides that, as a living being, he should have a name, and calls himself Johnny Five.

Fifth (Stargate SG-1): One of the few characters with an ordinal number for a name, Fifth gets his name in a fairly straightforward manner: he's the fifth human-form Replicator to be created on the planet Halla.

V (V for Vendetta): Most people who live through encounters with the mysterious anarchist V think they're addressing him by a letter, and his propensity for using V-based alliterations when introducing himself seems to confirm this. But it's much more likely that V derives his name from the source of his vendetta; when he was subjected to medical experimentation at the Larkhill Resettlement Camp, he was the man in room five — marked with the Roman numeral "V."

Number Six (The Prisoner): Residents of the mysterious Village are known by a number rather than their actual names — including at least 16 individuals known only as "Number Two" — probably to protect the secrets they all inevitably carry. Number Six, the titular prisoner, protests in the opening that he's a free man, not a number, but it's implied that Number Six may be known by yet another number: Number One.

The Cylons (Battlestar Galactica): The creators of Battlestar Galactica have said that cylon Number Six is a tribute to The Prisoner, and it follows that each humanoid cylon model would have its own number, with the notable exception of the Final Five. Most cylon models are known collectively by a human name as well (the Sharons, the Leobens, the D'Annas), but individual Sixes tend to have individual human names, like Natalie, Caprica, Shelly, and Gina, perhaps because of they are so often used as infiltration agents.

Seven of Nine (Voyager): Names designate individuality, a concept the Borg have no use for, but sometimes it is convenient for the Collective to identify individual Borg drones. So when the formerly human Annika Hansen was assimilated into the Collective, she was given the designation Seven of Nine, Tertiary Adjunct of Unimatrix Zero-One. Even once she was unhooked from the hive mind, she preferred the shortened "Seven of Nine" to her human name, the latter of which she does not take up again until her Borg implants are completely destroyed.

Eight (The Specials): It's fairly obvious how Eight earned its superhero name. A hive mind, Eight consists of eight individual bodies who can physically act independent of one another, but share a single consciousness.

Thirteen (House): As long as we're labeling House as science fiction, we may as well mention Dr. Remy Hadley, better known as Thirteen. In one of his trademark moves to dehumanize his fellowship applicants, Dr. House assigned each applicant a number (and occasionally a humiliating nickname). Thirteen really took to the numerical naming system, refusing to divulge her actual name to her fellow applicants, and continuing to answer to Thirteen long after she'd earned a place on House's team.

Henchmen 21 and 24 (The Venture Bros): With the exception of the ill-fated Speedy, each of the Monarch's henchman is known only to their boss as a number. Henchmen 21 and 24 (the former is known to his mom as Gary) are genre-savvy enough to be content with their numerical positions in the Fluttering Horde. When they learn their new teammate is Henchman 1, they rightly assess that he's marked for death.

84 (P.S. 238): In a school filled with superheroes, Julie Finster has a pretty routine set of superpowers: flight, invulnerability, speed. In fact, her power set is so ordinary that instead of getting a cool superhero name, she's just called "84," since she's the 84th person to possess that particular grouping of powers. Needless to say, it's a tad demoralizing.

Agent 99 (Get Smart): James Bond may have been called 007 from time to time, but Agent 99 takes use of her code number to the next level, never answering to any other moniker (okay, in one episode, her fiance calls her Susan Hilton, but that isn't actually her name). In fact, she married Maxwell Smart and bears him twins without him ever learning her real name, proving once and for all that she's the better spy.

Agent 355 (Y the Last Man): In the historical spy network known as the Culper Ring, there was a female agent code named 355, whose identity has never been definitively determined. Similarly, in the fictional Culper Ring of Y the Last Man, Agent 355 is a highly competent spy whose name is never revealed (at least not to the reader). Her odd relationship with her name parallels that of Alter Tse'elon, the Israel commando whose real first name is not spoken (until the end) for fear of attracting the Angel of Death.

Experiment 626 (Lilo and Stitch): The alien mad scientist Dr. Jumba Jookiba created 626 strange and dangerous lifeforms. The wanton destruction caused by the final experiment, 626, condemns them both to life in exile, but the experiment escapes to Earth, where a young Hawaiian girl names him "Stitch." Of course, once Stitch's destructive nature has been reigned in, there are still 625 other experiments to contend with.

1812 (Farscape): In terms of numbered names, the DRD robot 1812 gets his from a fairly unusual source. Instead of 1812 being a serial number or a numbered designation, it's a reference to the 1812 Overture, which Crichton teaches the little service bot to play.

Subject 781227 (Kyle XY): Zzyzx, the company funding Adam Baylin's research, saw the child-shaped being Adam Baylin developed in his lab as a biological computer rather than a person, reflected in him getting a serial number in lieu of a name. It's only after 16 years, an escape, and a bout of amnesia that Subject 781227 finally gets a name: Kyle Trager.

Playboys:

I think comics are one of the few places you still see men referred to as "playboys." Usually it's part of a phrase that also references their wealth, like "billionaire playboy Bruce Wayne." In any case, Bruce Wayne lives up to the term, bedding lots of supermodels as well as Talia Al Ghul, daughter of his arch-foe Ra's Al Ghul. When Grant Morrison took over writing Batman, he vowed to bring back "hairy-chested love god Batman," who really never left. Here's a whole article from the Long Island Voice complaining that "Batman Gets Laid Too Much." (They're uptight in Long Island, I guess.)

And then there's Tony Stark/Iron Man, who's portrayed as a total ladies' man in many of his comic-book appearances as well as his recent movie, where he seduces a hostile reporter in like 10 seconds flat.

I don't think Wolverine is a billionaire or even a millionaire, but he's hooked up with a lot of women in his time — there's one issue of Grant Morrison's New X-Men where he goes to Asia to fight some army of evil, and he meets a female mutant bad-ass ninja. A few pages later, they're off to bed together. It's part of Wolverine's mystique — his animalistic drive and beasty scent drive women wild, and his healing factor probably gives him incredible stamina. He's slept with everybody, including Black Widow. He's even had sex with the Scarlet Witch's mom (Magneto's wife) in The Ultimates.

Also, The Spirit, Will Eisner's pulpy detective/science hero/superhero, had women all over him, all the time, says Reading Comics author Douglas Wolk. Just look here. And here. And here. And Spider-Man gets his fair share of excitement, including dating a bunch of models and marrying a model/actress. He had the easiest divorce in history, courtesy of the Marvel Universe version of the Devil, and has been dating like a madman ever since. And Wally West, who took over as the Flash in the mid-1980s, was speeding through a series of one-night stands before he finally settled down with his wife Linda. Plus Luke Cage, aka the former Power Man, has scored with a number of superheroes in his time, and has been described as a big "Cape-Chaser" in Alias #6.

Other big comic-book playas include Batman's protege Nightwing, Green Arrow and his sidekick Red Arrow, and most of the Authority. There's a running subplot in recent issues of Green Lantern where John Stewart teases Hal Jordan (the original silver age Lantern) about his huge number of booty calls. And thanks to commenter Whitworthian for the list of all the women Daredevil has hooked up with.

Women of ill repute:

There's a great scene in a She Hulk comic where She Hulk goes to bed with Tony Stark, because why not? And afterwards, She Hulk and Tony have a whole conversation about the double standard: they both love having sex, with lots and lots of other people, but Tony gets to be a cool "stud," and she gets jeered at as a naughty slut. (The SHIELD helicarrier gets conveniently attacked before Tony can give a good answer.)

She Hulk's huge sexual appetite is a by-product of her Gamma-radiated superpowers, and it's a huge theme of Dan Slott's run on the comic: when she gets big and green, she gets really, really horny and has fewer inhibitions. She beds lots of male models and superheroes — but she protests that she never had sex with the Juggernaut. (The She Hulk-Juggernaut hook-up happened in a comic by reviled writer Chuck Austen.) Eventually she discovers that it was actually an alternate universe version of She-Hulk. But not before she hits on Wolverine, and he gives her shit about it. (Click to enlarge.)

In a similar vein, the poor Huntress gets all kinds of shit in Birds Of Prey, after she sleeps with her fellow hero Oracle's ex, and she sleeps with her fellow hero Black Canary's (sorta) step-son Speedy/Arsenal/Red Arrow. Says Black Canary, "Gee, Helena, maybe this would be easier if you'd just tell us who you haven't done the freak dance with?" (Later, Oracle and Canary apologize for slut-shaming Huntress — but not before Huntress has had sex with Josh the parking attendant whom she agreed to date in exchange for help on a mission.)

But Black Canary should totally not talk — she has hooked up with lots of guys during her single days, including the Ray, a teenage superhero whom she, ummm... took under her wing. (DC Comics' editors have since tried to claim the Canary-Ray hookup didn't happen, but it's right there on the page.) Another superhero woman who gets lots of nookie is Tesla Strong, daughter of Tom Strong.

Then there's The Pro, about a sex worker who gets superpowers from the all-powerful Viewer, and joins a thinly veiled parody of the Justice League. She's expelled for profanity, ultra-violence, and for giving the Saint (a Superman rip-off) a blow job.

Heroes Who Cheat:

In the movie The Specials, Ms. Indestructible proves that her sexual ethics aren't indestructible after all, by cheating on her husband the Strobe with his friend, the Weevil. Also, Scott Summers aka Cyclops cheats on his wife, Jean Grey, with the formerly evil Emma Frost — although only psychically, I think. Meanwhile, here's a guy who thinks Jean was looking at Wolverine a little too much — and he's really really really mad about it.

Also, the whole plot of Jay Faerber's Dynamo 5 series revolves around adultery — Captain Dynamo is a beloved protector of his native Tower City. But after he dies, it turns out he's slept with tons of women besides his wife — and he's had five kids by various mothers. Each one of the kids has inherited one of his superpowers, and they all have to team up to save the day.

Sexually transmitted superpowers:

Some superheroes actually get their superpowers in the sack — like the heroes of John Byrne's Next Men, mutants whose powers are triggered when they become sexually active with another superpowered person. (Because the teenagers, grown in a lab, are more innocent, they refer to sex as "dancing." Awww. They "dance" a lot, even after it's given them their superpowers already.)

Also, in OMAC #5, the OMAC nanovirus passes from Mike to Vienna when they hook up, giving her special robo-superpowers. In Alan Moore's Top Ten, there's the S.T.O.R.M.S. sexually transmitted disease, which either kills you or (in rare cases) gives you superpowers.

But my favorite is probably the novel The Bonds Of Love by J.M. Snyder, as described in this review:

Whenever Matt and Vic have sex, super-powers get conferred upon Vic. If you can think of a super-power, Vic has probably already experienced it: the ability to fly, self-heal, teleport, be invisible, or develop immense strength. Some powers are of dubious use: once his bones kept melting away, and he had to call in sick because he couldn't drive a bus with a boneless arm!

It turns out the powers originate with Matt, but he confers them onto Vic. Or something.

Okay, I'm sure I missed some incredibly awesome and obvious examples of superheroes whose booty calls outnumber their calls to adventure. (For one thing, there was an actual comic, Young Heroes In Love, all about superheroes' love lives, but it's a blur to me now.) Who else did I forget?

Thanks to Douglas Wolk, once again, for research help.

David Zucker has been producing and directing comedy movies sporadically since Airplane!, and most recently directed Scary Movie 3, 4, and 5. I suppose if you're on a roll, why not stick with what you know... but do people care anymore? I seriously kept waiting for something funny to happen in this trailer, thinking it would elicit at least one laugh. Well, I was wrong. It devolves quickly into tired jokes and a superhero getting partially pantsed. Whoa! You can see his skivvies! Haw haw. The trailer for Hancock had more laughs than this did. In fact, remember Will Smith talking to the mannequins in I Am Legend? That was comedy gold in comparison.

We don't want to see Leslie Nielsen brought to this. But at least now you know what Brent "Data" Spiner has been up to. Please tell us their next project isn't Science Fiction Movie.