<![CDATA[io9: vaccine]]> http://tags.lifehacker.com/assets/base/img/thumbs140x140/io9.com.png <![CDATA[io9: vaccine]]> http://io9.com/tag/vaccine http://io9.com/tag/vaccine <![CDATA[H1N1 Is a Plot to Kill Baby Boomers, Argues Conspiracy Theorist]]> A new day, a new H1N1 conspiracy theory! But this one is special. Ken Welch says on his blog, before treating us to an extremely detailed analysis:

We've recently learned the secret behind the Swine Flu Vaccine that is being pushed so strongly on the public. While the vaccine may make you sick, its real purpose is to greatly increase the fast-kill mechanism of the pandemic still to come. Worse yet, the vaccine is being used to target specific groups of people who are simply not welcome in our brave new world.

In the USA these include Blacks, American Indians, and Baby Boomers.

You know you have to read more now.

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<![CDATA[HIV Is Weaker Than We Think]]> Scientists have discovered antibodies that bind to a "weak spot" in the make up of HIV, leading to renewed hopes for the creation of a successful vaccine.

A team of researchers led by Dennis Burton of the Scripps Research Institute in La Jolla, California, discovered not only two "extremely potent" HIV antibodies, but also which part of the virus that the antibodies recognized, which was previously unknown as a binding site. Wayne Koff, senior vice president of research and development at the International AIDS Vaccine Initiative and member of the research team says,

It's the discovery of the target that's the key thing... Our hypothesis now is that if you bind to the [newly discovered target area], you neutralise the virus, as that's how it appears on the surface of the virus... The expectation is that we'll find more. We hope there will be a number of sites that are vulnerable, and we'll know that in a few months' time.

As well as continuing to look for more weak spots, scientists now have to create vaccines that will help others create the antibodies to fight the virus in future.

Discovery of HIV's weak spot boosts vaccine quest [New Scientist]

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<![CDATA[Get Your Malaria Vaccine Via Mosquito Bite]]> Malaria kills over a million people a year, mostly in Sub-Saharan Africa where the infected mosquito population is out of control. Now, epidemiologists are developing a radical new mechanism for vaccinating at-risk populations: through mosquito bites.

Researchers at Radboud University in Nijmegen, the Netherlands, staged a small proof-of-principle experiment, aimed at determining whether exposure to parasites, via insect bites, could vaccinate humans against malaria.

Knowing that humans can develop an immunity to malaria after repeated exposures and that the drug chloroquine kills malaria parasites in the late stages of infection, the researchers divided 15 subjects into two groups. They exposed the first group, periodically, to parasite-bearing mosquitoes and treated them with chloroquine. The second group, the researchers also treated with chloroquine, but didn't expose to the mosquitoes. All the volunteers stopped taking chloroquine and were later exposed to parasite-carrying mosquitoes. No members of the group previously exposed to malaria developed the disease; each member of the comparison group did.

Although it's a far cry from delivering an actual vaccine via insect — and seems more a call for widerspread distribution of antimalarial drugs — it does present the possibility that insects could someday be used to immunize populations against disease. With respect to pandemics like malaria, such a mechanism could be a lifesaver, but it also presents a profound ethical dilemma. The subjects in this test gave their consent to be infected, persons living among vaccine-carrying critters wouldn't have the same luxury.

Mosquitoes deliver malaria 'vaccine' through bites [AP via Slashdot]

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<![CDATA[Get Innoculated at Your Local Tattoo Vaccine Parlor]]> Tattoos may provide the vaccines of the future. A new study shows that using a vibrating tattoo needle to deliver vaccine produces 16 times more antibodies than a typical injection, which goes into muscle tissue. So will we be going down to our local tattoo parlors to get vaccine serum tattoos instead of ink? Not a bad idea, say the researchers. Vaccine tattoos could become the must-have biotech body mods of the twenty-first century.

According to the BBC:

Dr Martin Mueller, one of the researchers behind this work, says that the greater damage to the body caused by the tattoo needle may explain the better immune response. The scientists say that the tattoo needles would never be suitable for preventative vaccines, such as measles, in children as the pain would be too great.
Obviously it wouldn't work for kids, but this could be the perfect Tattoo 2.0 tech for a generation sick of boring old tattoos that do nothing but display static images. These tattoos actually have an effect on the health and chemistry of your body. Next up: drug tattoos.

Tattoos May Help Deliver Vaccine [BBC]

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<![CDATA[Harvesting the Saliva Glands of Mosquitoes]]> This dead mosquito's saliva glands are being harvested by researchers using two tiny syringes. They hope to use the insect's tainted spit to manufacture malaria vaccine more efficiently in the future. This delicate operation took place last month at Sanaria, Inc. in Maryland. Image by Tim Sloan for Getty.

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