Who's The Greatest Fictional Scientist Of All Time?

Everybody admires the explorers and action heroes, who go where nobody's gone before and set off explosions along the way. But what about the scientists, who invent the cool gear and form the theories that inform everything? Who's the absolute greatest scientist in all of science fiction?

Please include a video clip of your chosen scientist, if possible. And please let us know her/his name, where she/he appears, and why they're so excellent. Thanks!

Top image: Good news, everyone! Hubert Farnsworth from Futurama is a brilliant inventor with a great theoretical mind. And he gave us Witten's Dog. What's not to love?