Who's your favorite hero defined by his/her greatest setback?

Lots of heroes are known for their greatest triumphs. That time they saved the universe, or their amazing victory against overwhelming odds. But who's your favorite hero who's indelibly defined by his or her most punishing defeat?

Please share a picture or clip of this valiant loser. And let us know the book, comic, TV show or movie he/she comes from, and why this one setback is so all-defining. Thanks!

Image: Han Solo in Carbonite by William Beem